3FN1

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008641	molecular_function	ubiquitin-like modifier activating enzyme activity
A	0019781	molecular_function	NEDD8 activating enzyme activity
A	0045116	biological_process	protein neddylation

Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	16
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. WHPNItet.GeICLslL

Chain	Residue	Details
B	TRP105-LEU120

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	153
Details	Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10133","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23300442","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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