3FN1

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008641	molecular_function	ubiquitin-like modifier activating enzyme activity
A	0019781	molecular_function	NEDD8 activating enzyme activity
A	0045116	biological_process	protein neddylation

Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	16
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. WHPNItet.GeICLslL

Chain	Residue	Details
B	TRP105-LEU120

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133, ECO:0000305|PubMed:23300442

Chain	Residue	Details
B	GLU122

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