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PDB: 230 results

6UQL
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BU of 6uql by Molmil
Crystal structure of R471A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, GLYCEROL, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-21
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6V59
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BU of 6v59 by Molmil
Crystal structure of the diheme peroxidase BthA Y463M variant from Burkholderia thailandensis E264
Descriptor: CHLORIDE ION, Di-haem cytochrome c peroxidase family protein, GLYCEROL, ...
Authors:Cohen, S.E, Drennan, C.L.
Deposit date:2019-12-03
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.593 Å)
Cite:A Stable Ferryl Porphyrin at the Active Site of Y463M BthA.
J.Am.Chem.Soc., 142, 2020
6UOI
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BU of 6uoi by Molmil
Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with malonate
Descriptor: FE (III) ION, FE3-S4 CLUSTER, Fumarate hydratase 2, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-15
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQ9
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BU of 6uq9 by Molmil
Crystal structure of R421A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, GLYCEROL, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-18
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQM
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BU of 6uqm by Molmil
Crystal structure of R173A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, GLYCEROL, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-21
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UP9
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Crystal structure of T467A variant of cytosolic fumarate hydratase from Leishmania major in a complex with malonate
Descriptor: Fumarate hydratase 2, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-16
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UPO
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BU of 6upo by Molmil
Crystal structure of H334A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, IRON/SULFUR CLUSTER
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-18
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.113 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQ8
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BU of 6uq8 by Molmil
Crystal structure of R421A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate and malonate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, GLYCEROL, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-18
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.339 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UOJ
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BU of 6uoj by Molmil
Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with succinate
Descriptor: Fumarate hydratase 2, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-15
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UPM
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BU of 6upm by Molmil
Crystal structure of T467A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, GLYCEROL, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-17
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6VWY
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BU of 6vwy by Molmil
Crystal structure of C45G/T50C D. vulgaris carbon monoxide dehydrogenase (anaerobic)
Descriptor: Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, Fe(4)-Ni(1)-S(4) cluster, ...
Authors:Wittenborn, E.C, Drennan, C.L.
Deposit date:2020-02-20
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:The Solvent-Exposed Fe-S D-Cluster Contributes to Oxygen-Resistance inDesulfovibrio vulgarisNi-Fe Carbon Monoxide Dehydrogenase.
Acs Catalysis, 10, 2020
6VWZ
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BU of 6vwz by Molmil
Crystal structure of air-exposed C45G/T50C D. vulgaris carbon monoxide dehydrogenase (20 minute air exposure)
Descriptor: Carbon monoxide dehydrogenase, Fe(4)-Ni(1)-S(4) cluster, oxidized, ...
Authors:Wittenborn, E.C, Drennan, C.L.
Deposit date:2020-02-20
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:The Solvent-Exposed Fe-S D-Cluster Contributes to Oxygen-Resistance inDesulfovibrio vulgarisNi-Fe Carbon Monoxide Dehydrogenase.
Acs Catalysis, 10, 2020
6VXE
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BU of 6vxe by Molmil
Crystal structure of hydroxyproline dehydratase (HypD) from Clostridioides difficile with substrate trans-4-hydroxy-L-proline bound
Descriptor: 4-HYDROXYPROLINE, Trans-4-hydroxy-L-proline dehydratase
Authors:Backman, L.R.F, Drennan, C.L.
Deposit date:2020-02-21
Release date:2020-04-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.464 Å)
Cite:Molecular basis for catabolism of the abundant metabolitetrans-4-hydroxy-L-proline by a microbial glycyl radical enzyme.
Elife, 9, 2020
6W4X
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BU of 6w4x by Molmil
Holocomplex of E. coli class Ia ribonucleotide reductase with GDP and TTP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MU-OXO-DIIRON, ...
Authors:Kang, G, Taguchi, A, Stubbe, J, Drennan, C.L.
Deposit date:2020-03-11
Release date:2020-04-08
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex.
Science, 368, 2020
6VXC
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BU of 6vxc by Molmil
Crystal structure of hydroxyproline dehydratase (HypD) from Clostridioides difficile
Descriptor: GLYCEROL, Trans-4-hydroxy-L-proline dehydratase
Authors:Backman, L.R.F, Drennan, C.L.
Deposit date:2020-02-21
Release date:2020-04-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular basis for catabolism of the abundant metabolitetrans-4-hydroxy-L-proline by a microbial glycyl radical enzyme.
Elife, 9, 2020
6VUE
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BU of 6vue by Molmil
wild-type choline TMA lyase in complex with 1-methyl-1,2,3,6-tetrahydropyridin-3-ol
Descriptor: (3S)-1-methyl-1,2,3,6-tetrahydropyridin-3-ol, Choline trimethylamine-lyase, SODIUM ION
Authors:Ortega, M.A, Drennan, C.L.
Deposit date:2020-02-15
Release date:2020-11-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria.
Acs Med.Chem.Lett., 11, 2020
6VX0
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BU of 6vx0 by Molmil
Crystal structure of air-exposed C45G/T50C D. vulgaris carbon monoxide dehydrogenase (2 hour air exposure)
Descriptor: Carbon monoxide dehydrogenase, Fe(4)-Ni(1)-S(4) cluster, oxidized, ...
Authors:Wittenborn, E.C, Drennan, C.L.
Deposit date:2020-02-20
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The Solvent-Exposed Fe-S D-Cluster Contributes to Oxygen-Resistance inDesulfovibrio vulgarisNi-Fe Carbon Monoxide Dehydrogenase.
Acs Catalysis, 10, 2020
6VX1
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BU of 6vx1 by Molmil
Crystal structure of air-exposed C45G/T50C D. vulgaris carbon monoxide dehydrogenase (2 day air exposure)
Descriptor: Carbon monoxide dehydrogenase, Fe(4)-Ni(1)-S(4) cluster, oxidized, ...
Authors:Wittenborn, E.C, Drennan, C.L.
Deposit date:2020-02-20
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:The Solvent-Exposed Fe-S D-Cluster Contributes to Oxygen-Resistance inDesulfovibrio vulgarisNi-Fe Carbon Monoxide Dehydrogenase.
Acs Catalysis, 10, 2020
6X5K
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BU of 6x5k by Molmil
Crystal structure of CODH/ACS with carbon monoxide bound to the A-cluster
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CARBON MONOXIDE, Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha, ...
Authors:Cohen, S.E, Wittenborn, E.C, Hendrickson, R, Drennan, C.L.
Deposit date:2020-05-26
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase
Acs Catalysis, 10, 2020
6WTE
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BU of 6wte by Molmil
Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with cobalamin and [4Fe-4S] cluster bound
Descriptor: 1,2-ETHANEDIOL, B12-binding domain-containing protein, COBALAMIN, ...
Authors:Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J.
Deposit date:2020-05-02
Release date:2020-12-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Nat.Chem.Biol., 17, 2021
6WTF
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BU of 6wtf by Molmil
Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound
Descriptor: COBALAMIN, IRON/SULFUR CLUSTER, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, ...
Authors:Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J.
Deposit date:2020-05-02
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Nat.Chem.Biol., 17, 2021
1L1L
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BU of 1l1l by Molmil
CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE
Descriptor: RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE
Authors:Sintchak, M.D, Arjara, G, Kellogg, B.A, Stubbe, J, Drennan, C.L.
Deposit date:2002-02-18
Release date:2002-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer.
Nat.Struct.Biol., 9, 2002
1MJG
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BU of 1mjg by Molmil
CRYSTAL STRUCTURE OF BIFUNCTIONAL CARBON MONOXIDE DEHYDROGENASE/ACETYL-COA SYNTHASE(CODH/ACS) FROM MOORELLA THERMOACETICA (F. CLOSTRIDIUM THERMOACETICUM)
Descriptor: ACETATE ION, CARBON MONOXIDE DEHYDROGENASE BETA SUBUNIT, COPPER (I) ION, ...
Authors:Doukov, T.I, Iverson, T.M, Seravalli, J, Ragsdale, S.W, Drennan, C.L.
Deposit date:2002-08-27
Release date:2003-01-28
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase
Science, 298, 2002
3GJA
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BU of 3gja by Molmil
CytC3
Descriptor: ACETATE ION, CytC3
Authors:Wong, C, Drennan, C.L.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of an open active site conformation of nonheme iron halogenase CytC3
J.Am.Chem.Soc., 131, 2009
3I01
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BU of 3i01 by Molmil
Native structure of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase from Moorella thermoacetica, water-bound C-cluster.
Descriptor: ACETATE ION, COPPER (I) ION, Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha, ...
Authors:Kung, Y, Doukov, T.I, Drennan, C.L.
Deposit date:2009-06-24
Release date:2009-09-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystallographic snapshots of cyanide- and water-bound C-clusters from bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.
Biochemistry, 48, 2009

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