6VXE
Crystal structure of hydroxyproline dehydratase (HypD) from Clostridioides difficile with substrate trans-4-hydroxy-L-proline bound
Summary for 6VXE
| Entry DOI | 10.2210/pdb6vxe/pdb |
| Descriptor | Trans-4-hydroxy-L-proline dehydratase, 4-HYDROXYPROLINE (3 entities in total) |
| Functional Keywords | glycyl radical enzyme, hydroxyproline dehydratase, lyase |
| Biological source | Clostridioides difficile 70-100-2010 |
| Total number of polymer chains | 8 |
| Total formula weight | 732701.91 |
| Authors | Backman, L.R.F.,Drennan, C.L. (deposition date: 2020-02-21, release date: 2020-04-08, Last modification date: 2023-10-11) |
| Primary citation | Backman, L.R.,Huang, Y.Y.,Andorfer, M.C.,Gold, B.,Raines, R.T.,Balskus, E.P.,Drennan, C.L. Molecular basis for catabolism of the abundant metabolitetrans-4-hydroxy-L-proline by a microbial glycyl radical enzyme. Elife, 9:-, 2020 Cited by PubMed: 32180548DOI: 10.7554/eLife.51420 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.464 Å) |
Structure validation
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