6VXE

Crystal structure of hydroxyproline dehydratase (HypD) from Clostridioides difficile with substrate trans-4-hydroxy-L-proline bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Trans-4-hydroxy-L-proline dehydratase	polymer	809	91456.6	8	UniProt (A0A031WDE4) Pfam (PF02901) Pfam (PF01228)	Clostridioides difficile 70-100-2010	Glycyl radical enzyme,Hyp dehydratase, HypD
2	I, J, K, L, M... (A, B, C, D, E...)	4-HYDROXYPROLINE	non-polymer		131.1	8	Chemie (HYP)
3	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	1456	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 789 (UniProt: A0A031WDE4)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	731652.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1049.0
All*	Total formula weight	732701.9

*Water molecules are not included.