7ZC4
| Cryo-EM structure of POLRMT mutant. | Descriptor: | DNA-directed RNA polymerase, mitochondrial | Authors: | Das, H, Hallberg, B.M. | Deposit date: | 2022-03-25 | Release date: | 2023-02-01 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022
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7PZR
| Cryo-EM structure of POLRMT in free form. | Descriptor: | DNA-directed RNA polymerase, mitochondrial | Authors: | Das, H, Hallberg, B.M. | Deposit date: | 2021-10-13 | Release date: | 2022-11-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022
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7PZP
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8C2R
| SARS-CoV2 Omicron BA.1 spike in complex with CAB-A17 antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CAB-A17 antibody (HC), ... | Authors: | Das, H, Hallberg, B.M. | Deposit date: | 2022-12-22 | Release date: | 2024-05-22 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | SARS-CoV-2 omicron Spike (RBD) in complex with CAB-A17 antibody To Be Published
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8P5M
| SARS-CoV-2 Spike RBD in complex with Mab-23 (Fab) | Descriptor: | Mab-23 (Heavy chain variable domain), Mab-23 (Light chain variable domain), Spike protein S1 | Authors: | Das, H, Hallberg, B.M. | Deposit date: | 2023-05-24 | Release date: | 2024-06-05 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | SARS-CoV-2 Spike RBD in complex with Mab-23 (Fab domains) To Be Published
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8C0Y
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7NS6
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7NLL
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2JG9
| Crystallographic structure of human C1q globular heads (P1) | Descriptor: | CALCIUM ION, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, ... | Authors: | Paidassi, H, Tacnet-Delorme, P, Garlatti, V, Darnault, C, Ghebrehiwet, B, Gaboriaud, C, Arlaud, G.J, Frachet, P. | Deposit date: | 2007-02-09 | Release date: | 2008-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol., 180, 2008
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2JG8
| Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1q subcomponent subunit A, ... | Authors: | Paidassi, H, Tacnet-Delorme, P, Garlatti, V, Darnault, C, Ghebrehiwet, B, Gaboriaud, C, Arlaud, G.J, Frachet, P. | Deposit date: | 2007-02-09 | Release date: | 2008-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol., 180, 2008
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7A29
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6ZXN
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7B18
| SARS-CoV-spike bound to two neutralising nanobodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 VHH E, ... | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2020-11-24 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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7A25
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7B17
| SARS-CoV-spike RBD bound to two neutralising nanobodies. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama,SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama, Spike protein S1 | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2020-11-23 | Release date: | 2021-02-10 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (4.01 Å) | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape Science, 371, 2021
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7B14
| Nanobody E bound to Spike-RBD in a localized reconstruction | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2, Spike protein S1 | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2020-11-23 | Release date: | 2021-04-28 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape Science, 371, 2021
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8V4F
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8A99
| SARS Cov2 Spike in 1-up conformation complex with Fab47 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ... | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2022-06-28 | Release date: | 2023-05-10 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023
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8A94
| SARS CoV2 Spike in the 2-up state in complex with Fab47. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain Variable domain), ... | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2022-06-27 | Release date: | 2023-05-03 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023
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8A95
| SARS Cov2 Spike RBD in complex with Fab47 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ... | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2022-06-27 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023
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8Q5Y
| cryoEM structure of SARS-CoV2 Spike trimer in complex with Fab23 | Descriptor: | Monoclonal antibody Mab 23 (Heavy Chain), Monoclonal antibody Mab 23 (Light chain), Spike glycoprotein | Authors: | Hallberg, M, Das, H. | Deposit date: | 2023-08-10 | Release date: | 2024-07-17 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques. Nat Commun, 15, 2024
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8A96
| SARS Cov2 Spike RBD in complex with Fab47 | Descriptor: | Fab47 Heavy chain (variable domain), Fab47 Light chain (variable domain), Spike protein S1 | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2022-06-27 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023
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7KSG
| SARS-CoV-2 spike in complex with nanobodies E | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 glycoprotein, Spike glycoprotein | Authors: | Hallberg, B.M, Das, H. | Deposit date: | 2020-11-22 | Release date: | 2021-01-20 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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3O96
| Crystal Structure of Human AKT1 with an Allosteric Inhibitor | Descriptor: | 1-(1-(4-(7-phenyl-1H-imidazo[4,5-g]quinoxalin-6-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, RAC-alpha serine/threonine-protein kinase | Authors: | Voegtli, W.C, Wu, W.-I, Lord-Ondash, H.A, Dizon, F.P, Vigers, G.P.A, Brandhuber, B.J. | Deposit date: | 2010-08-03 | Release date: | 2010-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of human AKT1 with an allosteric inhibitor reveals a new mode of kinase inhibition. Plos One, 5, 2010
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1AXD
| STRUCTURE OF GLUTATHIONE S-TRANSFERASE-I BOUND WITH THE LIGAND LACTOYLGLUTATHIONE | Descriptor: | GLUTATHIONE S-TRANSFERASE I, LACTOYLGLUTATHIONE | Authors: | Neuefeind, T, Huber, R, Dasenbrock, H, Prade, L, Bieseler, B. | Deposit date: | 1997-10-15 | Release date: | 1998-10-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of herbicide-detoxifying maize glutathione S-transferase-I in complex with lactoylglutathione: evidence for an induced-fit mechanism. J.Mol.Biol., 274, 1997
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