6ZXN

Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing nanobodies (Ty1)

Summary for 6ZXN

• Entry DOI: 10.2210/pdb6zxn/pdb
• EMDB information: 11526
• Descriptor: Spike glycoprotein, Nanobody Ty1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sars-cov-2, spike protein, neutralising antibody, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 483838.82

Authors

Hallberg, B.M.,Das, H. (deposition date: 2020-07-30, release date: 2020-09-23)

• Primary citation: Hanke, L.,Vidakovics Perez, L.,Sheward, D.J.,Das, H.,Schulte, T.,Moliner-Morro, A.,Corcoran, M.,Achour, A.,Karlsson Hedestam, G.B.,Hallberg, B.M.,Murrell, B.,McInerney, G.M.; An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.; Nat Commun, 11:4420-4420, 2020; PubMed: 32887876; DOI: 10.1038/s41467-020-18174-5

Experimental method

ELECTRON MICROSCOPY (2.93 Å)