7JUN
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2KHC
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6VH7
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![BU of 6vh7 by Molmil](/molmil-images/mine/6vh7) | Doublet Tau Fibril from Corticobasal Degeneration Human Brain Tissue | 分子名称: | Microtubule-associated protein tau | 著者 | Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P. | 登録日 | 2020-01-09 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180, 2020
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7JTH
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7JOM
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6UO7
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6V0T
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![BU of 6v0t by Molmil](/molmil-images/mine/6v0t) | Crystal Structure of Catalytic Subunit of Bovine Pyruvate Dehydrogenase Phosphatase 1 - Catalytic Domain | 分子名称: | MANGANESE (II) ION, SULFATE ION, [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, ... | 著者 | Guo, Y, Qiu, W, Ernst, S.R, Carroll, D.W, Hackert, M.L. | 登録日 | 2019-11-19 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the catalytic subunit of bovine pyruvate dehydrogenase phosphatase. Acta Crystallogr.,Sect.F, 76, 2020
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6V0K
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6V7A
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![BU of 6v7a by Molmil](/molmil-images/mine/6v7a) | Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (CD2) complexed with NF2657 | 分子名称: | Hdac6 protein, N-hydroxy-4-[(1-methyl-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)methyl]benzamide, POTASSIUM ION, ... | 著者 | Osko, J.D, Christianson, D.W. | 登録日 | 2019-12-08 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.0874176 Å) | 主引用文献 | Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation. Acs Med.Chem.Lett., 11, 2020
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7KJG
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![BU of 7kjg by Molmil](/molmil-images/mine/7kjg) | F96M epi-isozizaene synthase: complex with 3 Mg2+ and BTAC | 分子名称: | GLYCEROL, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ... | 著者 | Ronnebaum, T.A, Gardner, S.M, Christianson, D.W. | 登録日 | 2020-10-26 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | An Aromatic Cluster in the Active Site of epi -Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways. Biochemistry, 59, 2020
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7KJD
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![BU of 7kjd by Molmil](/molmil-images/mine/7kjd) | F96M epi-isozizaene synthase: complex with 3 Mg2+ and risedronate | 分子名称: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, MAGNESIUM ION, SULFATE ION, ... | 著者 | Ronnebaum, T.A, Gardner, S.M, Christianson, D.W. | 登録日 | 2020-10-26 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | An Aromatic Cluster in the Active Site of epi -Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways. Biochemistry, 59, 2020
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7KUS
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![BU of 7kus by Molmil](/molmil-images/mine/7kus) | Crystal Structure of Danio rerio Histone Deacetylase 10 H137A Mutant in Complex with N8-Acetylspermidine (Tetrahedral Intermediate) | 分子名称: | 1,2-ETHANEDIOL, 1-({4-[(3-aminopropyl)amino]butyl}amino)ethane-1,1-diol, DI(HYDROXYETHYL)ETHER, ... | 著者 | Herbst-Gervasoni, C.J, Christianson, D.W. | 登録日 | 2020-11-25 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60, 2021
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7KJF
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![BU of 7kjf by Molmil](/molmil-images/mine/7kjf) | Wild-type epi-isozizaene synthase: complex with 3 Mg2+ and neridronate | 分子名称: | (6-azanyl-1-oxidanyl-1-phosphono-hexyl)phosphonic acid, GLYCEROL, MAGNESIUM ION, ... | 著者 | Ronnebaum, T.A, Gardner, S.M, Christianson, D.W. | 登録日 | 2020-10-26 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | An Aromatic Cluster in the Active Site of epi -Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways. Biochemistry, 59, 2020
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6VHA
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![BU of 6vha by Molmil](/molmil-images/mine/6vha) | Singlet Tau Fibril from Corticobasal Degeneration Human Brain Tissue | 分子名称: | Microtubule-associated protein tau | 著者 | Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P. | 登録日 | 2020-01-09 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180, 2020
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7KUQ
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7KJ9
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![BU of 7kj9 by Molmil](/molmil-images/mine/7kj9) | Wild-type epi-isozizaene synthase: complex with 3 Mg2+ and risedronate | 分子名称: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, MAGNESIUM ION, SULFATE ION, ... | 著者 | Ronnebaum, T.A, Gardner, S.M, Christianson, D.W. | 登録日 | 2020-10-26 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | An Aromatic Cluster in the Active Site of epi -Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways. Biochemistry, 59, 2020
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7KUR
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7KJE
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![BU of 7kje by Molmil](/molmil-images/mine/7kje) | F96S epi-isozizaene synthase: complex with 3 Mg2+ and neridronate | 分子名称: | (6-azanyl-1-oxidanyl-1-phosphono-hexyl)phosphonic acid, MAGNESIUM ION, SULFATE ION, ... | 著者 | Ronnebaum, T.A, Gardner, S, Christianson, D.W. | 登録日 | 2020-10-26 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An Aromatic Cluster in the Active Site of epi -Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways. Biochemistry, 59, 2020
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7KUT
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![BU of 7kut by Molmil](/molmil-images/mine/7kut) | Crystal Structure of Danio rerio Histone Deacetylase 10 H137A Mutant in Complex with N-Acetylputrescine (Tetrahedral Intermediate) | 分子名称: | 1,2-ETHANEDIOL, 1-[(4-aminobutyl)amino]ethane-1,1-diol, DI(HYDROXYETHYL)ETHER, ... | 著者 | Herbst-Gervasoni, C.J, Christianson, D.W. | 登録日 | 2020-11-25 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60, 2021
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6UOC
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![BU of 6uoc by Molmil](/molmil-images/mine/6uoc) | Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) K330L mutant complexed with Givinostat | 分子名称: | 1,2-ETHANEDIOL, Givinostat, Histone deacetylase 6, ... | 著者 | Osko, J.D, Christianson, D.W. | 登録日 | 2019-10-14 | 公開日 | 2019-12-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.400008 Å) | 主引用文献 | Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6. Biochemistry, 58, 2019
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6UOB
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![BU of 6uob by Molmil](/molmil-images/mine/6uob) | Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) K330L mutant complexed with Resminostat | 分子名称: | 1,2-ETHANEDIOL, Histone deacetylase 6, PHENYLALANINE, ... | 著者 | Osko, J.D, Christianson, D.W. | 登録日 | 2019-10-14 | 公開日 | 2019-12-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.58000576 Å) | 主引用文献 | Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6. Biochemistry, 58, 2019
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6UQD
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7KUV
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7L1F
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7KJ8
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![BU of 7kj8 by Molmil](/molmil-images/mine/7kj8) | Wild-type epi-isozizaene synthase: complex with 3 Mg2+ and pamidronate | 分子名称: | MAGNESIUM ION, PAMIDRONATE, SULFATE ION, ... | 著者 | Ronnebaum, T.A, Gardner, S.M, Christianson, D.W. | 登録日 | 2020-10-26 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | An Aromatic Cluster in the Active Site of epi -Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways. Biochemistry, 59, 2020
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