6UO7

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) K330L mutant complexed with AR-42

Summary for 6UO7

Entry DOI	10.2210/pdb6uo7/pdb
Descriptor	Histone deacetylase 6, ZINC ION, POTASSIUM ION, ... (5 entities in total)
Functional Keywords	histone deacetylase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	1
Total formula weight	40734.54
Authors	Osko, J.D.,Christianson, D.W. (deposition date: 2019-10-14, release date: 2019-12-04, Last modification date: 2023-10-11)
Primary citation	Osko, J.D.,Christianson, D.W. Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6. Biochemistry, 58:4912-4924, 2019 Cited by PubMed: 31755702 DOI: 10.1021/acs.biochem.9b00934 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.39501316141 Å)

Structure validation