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6UO7

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) K330L mutant complexed with AR-42

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Histone deacetylase 6polymer36640278.61UniProt (F8W4B7)
Pfam (PF00850)
Danio rerio (Zebrafish)
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C, D
(A)
POTASSIUM IONnon-polymer39.12Chemie (K)
4E
(A)
AR-42non-polymer312.41Chemie (QCP)
5F
(A)
waterwater18.0384Chemie (HOH)
Sequence modifications
A: 60 - 419 (UniProt: F8W4B7)
PDBExternal DatabaseDetails
Ser 54-expression tag
Asn 55-expression tag
Ala 56-expression tag
Gly 57-expression tag
Gly 58-expression tag
Ser 59-expression tag
Leu 330Lys 330engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40278.6
Non-Polymers*Number of molecules4
Total formula weight456.0
All*Total formula weight40734.5
*Water molecules are not included.

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PDB entries from 2025-07-30

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