7KJG

F96M epi-isozizaene synthase: complex with 3 Mg2+ and BTAC

Summary for 7KJG

Entry DOI	10.2210/pdb7kjg/pdb
Descriptor	epi-isozizaene synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... (7 entities in total)
Functional Keywords	terpene cyclase, complex, bisphosphonate inhibitor, risedronate, lyase
Biological source	Streptomyces coelicolor
Total number of polymer chains	1
Total formula weight	44329.39
Authors	Ronnebaum, T.A.,Gardner, S.M.,Christianson, D.W. (deposition date: 2020-10-26, release date: 2020-12-16, Last modification date: 2023-10-18)
Primary citation	Ronnebaum, T.A.,Gardner, S.M.,Christianson, D.W. An Aromatic Cluster in the Active Site of epi -Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways. Biochemistry, 59:4744-4754, 2020 Cited by PubMed: 33270439 DOI: 10.1021/acs.biochem.0c00876 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation