2VRT
 
 | | Crystal Structure of E. coli RNase E possessing M1 RNA fragments - Catalytic Domain | | 分子名称: | 5'-R(*UP*UP)-3', 5'-R(*UP*UP*GP)-3', RIBONUCLEASE E, ... | | 著者 | Koslover, D.J, Callaghan, A.J, Marcaida, M.J, Garman, E.F, Martick, M, Scott, W.G, Luisi, B.F. | | 登録日 | 2008-04-14 | | 公開日 | 2008-07-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
Structure, 16, 2008
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5IW5
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5IXK
 | | RORgamma in complex with inverse agonist BIO399. | | 分子名称: | N-(5-ethyl-3,3-dimethyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-8-yl)-3,4-dimethyl-N-(2,2,2-trifluoroethyl)benzene-1-sulfonamide, Nuclear receptor ROR-gamma | | 著者 | Marcotte, D.J. | | 登録日 | 2016-03-23 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand.
Bmc Struct.Biol., 16, 2016
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2VSE
 | | Structure and mode of action of a mosquitocidal holotoxin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, MOSQUITOCIDAL TOXIN | | 著者 | Treiber, N, Reinert, D.J, Carpusca, I, Aktories, K, Schulz, G.E. | | 登録日 | 2008-04-22 | | 公開日 | 2008-07-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Mode of Action of a Mosquitocidal Holotoxin.
J.Mol.Biol., 381, 2008
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5I68
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5INZ
 | | Racemic structure of baboon theta defensin-2 | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Theta defensin-2, ... | | 著者 | Wang, C.K, King, G.J, Conibear, A.C, Ramos, M.C, Craik, D.J. | | 登録日 | 2016-03-08 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.447 Å) | | 主引用文献 | Mirror Images of Antimicrobial Peptides Provide Reflections on Their Functions and Amyloidogenic Properties.
J.Am.Chem.Soc., 138, 2016
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2WRB
 | | the structure of influenza H2 human singapore hemagglutinin with avian receptor | | 分子名称: | HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid | | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2009-09-01 | | 公開日 | 2009-09-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2WRE
 | | structure of H2 japan hemagglutinin with human receptor | | 分子名称: | HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2009-09-01 | | 公開日 | 2009-09-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
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5J5S
 | | Src kinase in complex with a sulfonamide inhibitor | | 分子名称: | N-{4-[8-amino-3-(propan-2-yl)imidazo[1,5-a]pyrazin-1-yl]naphthalen-1-yl}-N'-[3-(trifluoromethyl)phenyl]urea, Proto-oncogene tyrosine-protein kinase Src | | 著者 | Lebedev, I, Feldman, H.C, Georghiou, G, Maly, D.J, Seeliger, M. | | 登録日 | 2016-04-03 | | 公開日 | 2016-06-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.153 Å) | | 主引用文献 | Structural and Functional Analysis of the Allosteric Modulation of IRE1a with ATP-Competitive Kinase Inhibitors
To Be Published
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2WR1
 | | structure of influenza H2 hemagglutinin with human receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, ... | | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2009-08-29 | | 公開日 | 2009-09-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
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5FLL
 | | Crystal structure of the 6-carboxyhexanoate-CoA ligase (BioW) from Bacillus subtilis in complex with a Pimeloyl-adenylate | | 分子名称: | 6-CARBOXYHEXANOATE-COA LIGASE, MAGNESIUM ION, PIMELOYL-AMP, ... | | 著者 | Moynie, L, Wang, M, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2015-10-26 | | 公開日 | 2016-11-16 | | 最終更新日 | 2018-06-13 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
Nat. Chem. Biol., 13, 2017
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2WRC
 | | the structure of influenza H2 human singapore hemagglutinin | | 分子名称: | HEMAGGLUTININ | | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2009-09-01 | | 公開日 | 2009-09-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.706 Å) | | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2Y37
 | | The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS) | | 分子名称: | 2-[(1R)-3-amino-1-phenyl-propoxy]-4-chloro-benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... | | 著者 | Cheshire, D.R, Andrews, G, Beaton, H.G, Birkinshaw, T.N, Boughton-Smith, N, Connolly, S, Cook, T.R, Cooper, A, Cooper, S.L, Cox, D, Dixon, J, Gensmantel, N, Hamley, P.J, Harrison, R, Hartopp, P, Kack, H, Luker, T, Mete, A, Millichip, I, Nicholls, D.J, Pimm, A.D, St-Gallay, S.A, Wallace, A.V. | | 登録日 | 2010-12-19 | | 公開日 | 2011-04-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos).
Bioorg.Med.Chem.Lett., 21, 2011
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7NNU
 | | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs | | 分子名称: | Conserved hypothetical membrane protein, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ... | | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2021-02-25 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NNT
 | | Cryo-EM structure of the folate-specific ECF transporter complex in DDM micelles | | 分子名称: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | | 登録日 | 2021-02-25 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5FJW
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5IZ0
 | | RORgamma in complex with agonist BIO592 and Coactivator EBI96 | | 分子名称: | CHLORIDE ION, GLU-PHE-PRO-TYR-LEU-LEU-SER-LEU-LEU-GLY-GLU-VAL-SER-PRO-GLN, N-(4-ethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-3,4-dimethyl-N-(2,2,2-trifluoroethyl)benzene-1-sulfonamide, ... | | 著者 | Marcotte, D.J. | | 登録日 | 2016-03-24 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.635 Å) | | 主引用文献 | Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand.
Bmc Struct.Biol., 16, 2016
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7NGH
 | | Structure of glutamate transporter homologue in complex with Sybody | | 分子名称: | ASPARTIC ACID, Proton/glutamate symporter, SDF family, ... | | 著者 | Arkhipova, V, Slotboom, D.J, Guskov, A. | | 登録日 | 2021-02-09 | | 公開日 | 2021-09-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Kinetic mechanism of Na + -coupled aspartate transport catalyzed by Glt Tk .
Commun Biol, 4, 2021
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5FQG
 | | The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens | | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-beta-D-galactopyranose, BETA-N-ACETYLGALACTOSAMINIDASE, FORMIC ACID | | 著者 | Noach, I, Pluvinage, B, Laurie, C, Abe, K.T, Alteen, M, Vocadlo, D.J, Boraston, A.B. | | 登録日 | 2015-12-10 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium Perfringens
J.Mol.Biol., 428, 2016
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5FPI
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5IW4
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5FKY
 | | Structure of a hydrolase bound with an inhibitor | | 分子名称: | (3aR,5R,6S,7R,7aR)-2-amino-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, GLYCEROL, O-GLCNACASE BT_4395 | | 著者 | Cekic, N, Heinonen, J.E, Stubbs, K.A, Roth, C, McEachern, E.J, Davies, G.J, Vocadlo, D.J. | | 登録日 | 2015-10-20 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by humanO-GlcNAcase.
Chem Sci, 7, 2016
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7NQG
 | | The structure of the SBP TarP_Rhp in complex with 4-hydroxyphenylacetate | | 分子名称: | 1,2-ETHANEDIOL, 4-HYDROXYPHENYLACETATE, PHOSPHATE ION, ... | | 著者 | Bisson, C, Salmon, R.C, West, L, Rafferty, J.B, Hitchcock, A, Thomas, G.H, Kelly, D.J. | | 登録日 | 2021-03-01 | | 公開日 | 2021-10-06 | | 最終更新日 | 2022-01-26 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | The structural basis for high-affinity uptake of lignin-derived aromatic compounds by proteobacterial TRAP transporters.
Febs J., 289, 2022
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5IXA
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5FLG
 | | Crystal structure of the 6-carboxyhexanoate-CoA ligase (BioW)from Bacillus subtilis in complex with AMPPNP | | 分子名称: | 6-CARBOXYHEXANOATE--COA LIGASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Moynie, L, Wang, M, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2015-10-26 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
Nat. Chem. Biol., 13, 2017
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