4GYW
 
 | | Crystal structure of human O-GlcNAc Transferase in complex with UDP and a glycopeptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Casein kinase II subunit alpha, SULFATE ION, ... | | 著者 | Lazarus, M.B, Jiang, J, Gloster, T.M, Zandberg, W.F, Vocadlo, D.J, Walker, S. | | 登録日 | 2012-09-05 | | 公開日 | 2012-10-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural snapshots of the reaction coordinate for O-GlcNAc transferase.
Nat.Chem.Biol., 8, 2012
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4EBV
 | | Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor | | 分子名称: | 8-(4-ethylphenyl)-5-methyl-2,5-dihydropyrazolo[4,3-c][2,1]benzothiazine 4,4-dioxide, Focal adhesion kinase 1, ISOPROPYL ALCOHOL | | 著者 | Skene, R.J, Hosfield, D.J. | | 登録日 | 2012-03-25 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Discovery and characterization of novel allosteric FAK inhibitors.
Eur.J.Med.Chem., 61, 2013
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7SVL
 | | DPP9 IN COMPLEX WITH LIGAND ICeD-2 | | 分子名称: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 9 | | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | | 登録日 | 2021-11-19 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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7TB1
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4EN5
 | | Crystal structure of fluoride riboswitch, Tl-Acetate soaked | | 分子名称: | FLUORIDE ION, Fluoride riboswitch, MAGNESIUM ION, ... | | 著者 | Ren, A.M, Rajashankar, K.R, Patel, D.J. | | 登録日 | 2012-04-12 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.957 Å) | | 主引用文献 | Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
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4ENA
 | | Crystal structure of fluoride riboswitch, soaked in Cs+ | | 分子名称: | CESIUM ION, FLUORIDE ION, Fluoride riboswitch, ... | | 著者 | Ren, A.M, Rajashankar, K.R, Patel, D.J. | | 登録日 | 2012-04-12 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
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7T8N
 | | Crystal structure of the PNAG binding module PgaA-TPR 220-359 | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Poly-beta-1,6-N-acetyl-D-glucosamine export protein | | 著者 | Pfoh, R, Little, D.J, Howell, P.L. | | 登録日 | 2021-12-16 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The TPR domain of PgaA is a multifunctional scaffold that binds PNAG and modulates PgaB-dependent polymer processing.
Plos Pathog., 18, 2022
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1Q8L
 | | Second Metal Binding Domain of the Menkes ATPase | | 分子名称: | Copper-transporting ATPase 1 | | 著者 | Jones, C.E, Daly, N.L, Cobine, P.A, Craik, D.J, Dameron, C.T. | | 登録日 | 2003-08-21 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and metal binding studies of the second copper binding domain of the Menkes ATPase.
J.Struct.Biol., 143, 2003
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201D
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202D
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2ANR
 | | Crystal structure (II) of Nova-1 KH1/KH2 domain tandem with 25nt RNA hairpin | | 分子名称: | 5'-R(*CP*(5BU)P*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*AP*AP*GP*CP*GP*AP*G)-3', MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Malinina, L, Teplova, M, Musunuru, K, Teplov, A, Darnell, J.C, Burley, S.K, Darnell, R.B, Patel, D.J. | | 登録日 | 2005-08-11 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
Structure, 19, 2011
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2ARU
 | | Crystal structure of lipoate-protein ligase A bound with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Lipoate-protein ligase A, MAGNESIUM ION | | 著者 | Kim, D.J, Kim, K.H, Lee, H.H, Lee, S.J, Ha, J.Y, Yoon, H.J, Suh, S.W. | | 登録日 | 2005-08-22 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains
J.Biol.Chem., 280, 2005
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2ASL
 | | oxoG-modified Postinsertion Binary Complex | | 分子名称: | 5'-D(*CP*T*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DOC))-3', CALCIUM ION, ... | | 著者 | Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J. | | 登録日 | 2005-08-23 | | 公開日 | 2006-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
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1QIC
 | | CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN | | 分子名称: | CALCIUM ION, PROTEIN (STROMELYSIN-1), ZINC ION | | 著者 | Williams, M.G, Ye, Q.-Z, Molina, F, Johnson, L.L, Ortwine, D.F, Pavlovsky, A.G, Rubin, J.R, Skeean, R.W, White, A.D, Blundell, T.L, Humblet, C, Hupe, D.J, Dhanaraj, V. | | 登録日 | 1999-06-11 | | 公開日 | 2003-02-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
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2AXE
 | | IODINATED COMPLEX OF ACETYL XYLAN ESTERASE AT 1.80 ANGSTROMS | | 分子名称: | ACETYL XYLAN ESTERASE, SULFATE ION | | 著者 | Ghosh, D, Erman, M, Sawicki, M.W, Lala, P, Weeks, D.R, Li, N, Pangborn, W, Thiel, D.J, Jornvall, H, Eyzaguirre, J. | | 登録日 | 1998-09-01 | | 公開日 | 1999-05-18 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase.
Acta Crystallogr.,Sect.D, 55, 1999
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1QO8
 | | The structure of the open conformation of a flavocytochrome c3 fumarate reductase | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C3 FUMARATE REDUCTASE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Bamford, V, Dobbin, P.S, Richardson, D.J, Hemmings, A.M. | | 登録日 | 1999-11-04 | | 公開日 | 2000-11-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Open Conformation of a Flavocytochrome C3 Fumarate Reductase.
Nat.Struct.Biol., 6, 1999
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2B38
 | | Solution structure of kalata B8 | | 分子名称: | kalata B8 | | 著者 | Daly, N.L, Clark, R.J, Plan, M.R, Craik, D.J. | | 登録日 | 2005-09-19 | | 公開日 | 2006-01-31 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif
Biochem.J., 393, 2006
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6R0X
 | | The extracellular domain of G6b-B in complex with Fab fragment and DP12 heparin oligosaccharide. | | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Megakaryocyte and platelet inhibitory receptor G6b, antibody fab fragment heavy chain, ... | | 著者 | Ogg, D.J, McMiken, H.J, Howard, T.D. | | 登録日 | 2019-03-13 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B.
Elife, 8, 2019
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2BAS
 | | Crystal Structure of the Bacillus subtilis YkuI Protein, with an EAL Domain. | | 分子名称: | BETA-MERCAPTOETHANOL, YkuI protein | | 著者 | Minasov, G, Brunzelle, J.S, Shuvalova, L, Miller, D.J, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-10-14 | | 公開日 | 2005-11-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Crystal structures of YkuI and its complex with second messenger cyclic Di-GMP suggest catalytic mechanism of phosphodiester bond cleavage by EAL domains.
J.Biol.Chem., 284, 2009
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6RVX
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7TVE
 | | ATP and DNA bound SMC5/6 core complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (68-MER), DNA (78-MER), ... | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2022-02-04 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1RUZ
 | | 1918 H1 Hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | | 著者 | Skehel, J.J, Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S. | | 登録日 | 2003-12-12 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
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1RW2
 | | Three-dimensional structure of Ku80 CTD | | 分子名称: | ATP-dependent DNA helicase II, 80 kDa subunit | | 著者 | Zhang, Z, Hu, W, Cano, L, Lee, T.D, Chen, D.J, Chen, Y. | | 登録日 | 2003-12-15 | | 公開日 | 2003-12-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions.
STRUCTURE, 12, 2004
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243D
 | | STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2 | | 分子名称: | DNA (5'-D(*AP*CP*GP*TP*AP*CP*GP*T)-3') | | 著者 | Wilcock, D.J, Adams, A, Cardin, C.J, Wakelin, L.P.G. | | 登録日 | 1996-01-10 | | 公開日 | 1996-02-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the DNA octanucleotide d(ACGTACGT)2.
Acta Crystallogr.,Sect.D, 52, 1996
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4GSL
 | | Crystal structure of an Atg7-Atg3 crosslinked complex | | 分子名称: | Autophagy-related protein 3, Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION | | 著者 | Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A. | | 登録日 | 2012-08-27 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | | 主引用文献 | Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Nat.Struct.Mol.Biol., 19, 2012
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