4GYW

Crystal structure of human O-GlcNAc Transferase in complex with UDP and a glycopeptide

Summary for 4GYW

• Entry DOI: 10.2210/pdb4gyw/pdb
• Related: 4GYY 4GZ3 4GZ5 4GZ6
• Descriptor: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, Casein kinase II subunit alpha, URIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: gt-b, glycosyltransferase, glcnacylation, transferase-peptide complex, transferase/peptide
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 166285.07

Authors

Lazarus, M.B.,Jiang, J.,Gloster, T.M.,Zandberg, W.F.,Vocadlo, D.J.,Walker, S. (deposition date: 2012-09-05, release date: 2012-10-31, Last modification date: 2020-07-29)

• Primary citation: Lazarus, M.B.,Jiang, J.,Gloster, T.M.,Zandberg, W.F.,Whitworth, G.E.,Vocadlo, D.J.,Walker, S.; Structural snapshots of the reaction coordinate for O-GlcNAc transferase.; Nat.Chem.Biol., 8:966-968, 2012; PubMed: 23103939; DOI: 10.1038/nchembio.1109

Experimental method

X-RAY DIFFRACTION (1.7 Å)