4GYW
Crystal structure of human O-GlcNAc Transferase in complex with UDP and a glycopeptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 723 | 80974.5 | 2 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) In PDB | Homo sapiens (human) | O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT |
2 | B, D | Casein kinase II subunit alpha | polymer | 14 | 1398.6 | 2 | UniProt (P68400) In PDB | Homo sapiens | CK II alpha |
3 | A, C | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
4 | A, B, D | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
5 | B, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
6 | water | water | 18.0 | 970 | Chemie (HOH) |
Sequence modifications
A, C: 313 - 1031 (UniProt: O15294)
B, D: 14 - 26 (UniProt: P68400)
PDB | External Database | Details |
---|---|---|
Gly 309 | - | expression tag |
Pro 310 | - | expression tag |
Gly 311 | - | expression tag |
Ser 312 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Tyr 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 164746.1 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1538.9 | |
All* | Total formula weight | 166285.1 |