6REI
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![BU of 6rei by Molmil](/molmil-images/mine/6rei) | Crystal structure of Pizza6-S with Cd2+ | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Artificial beta-Propeller Protein-based Hydrolases To Be Published
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6REM
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![BU of 6rem by Molmil](/molmil-images/mine/6rem) | Crystal structure of Pizza6-SH with Sulphate ion | Descriptor: | Pizza6-SH, SULFATE ION | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Artificial beta-Propeller Protein-based Hydrolases To Be Published
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1KIY
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![BU of 1kiy by Molmil](/molmil-images/mine/1kiy) | D100E trichodiene synthase | Descriptor: | 1,2-ETHANEDIOL, trichodiene synthase | Authors: | Rynkiewicz, M.J, Cane, D.E, Christianson, D.W. | Deposit date: | 2001-12-03 | Release date: | 2002-03-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray crystal structures of D100E trichodiene synthase and its pyrophosphate complex reveal the basis for terpene product diversity. Biochemistry, 41, 2002
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1KEZ
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![BU of 1kez by Molmil](/molmil-images/mine/1kez) | Crystal Structure of the Macrocycle-forming Thioesterase Domain of Erythromycin Polyketide Synthase (DEBS TE) | Descriptor: | ERYTHRONOLIDE SYNTHASE | Authors: | Tsai, S.-C, Miercke, L.J.W, Krucinski, J, Gokhale, R, Chen, J.C.-H, Foster, P.G, Cane, D.E, Khosla, C, Stroud, R.M. | Deposit date: | 2001-11-19 | Release date: | 2002-01-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel. Proc.Natl.Acad.Sci.USA, 98, 2001
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6REL
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![BU of 6rel by Molmil](/molmil-images/mine/6rel) | Crystal structure of Pizza6-SH with CdCl2 nanocrystal | Descriptor: | CADMIUM ION, CHLORIDE ION, Pizza6-SH | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Artificial beta-Propeller Protein-based Hydrolases To Be Published
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1KRW
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![BU of 1krw by Molmil](/molmil-images/mine/1krw) | SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF BERYLLOFLUORIDE-ACTIVATED NTRC RECEIVER DOMAIN | Descriptor: | NITROGEN REGULATION PROTEIN NR(I) | Authors: | Hastings, C.A, Lee, S.-Y, Cho, H.S, Yan, D, Kustu, S, Wemmer, D.E. | Deposit date: | 2002-01-10 | Release date: | 2003-08-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | High-Resolution Solution Structure of the Beryllofluoride-Activated NtrC Receiver Domain Biochemistry, 42, 2003
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1DC7
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![BU of 1dc7 by Molmil](/molmil-images/mine/1dc7) | STRUCTURE OF A TRANSIENTLY PHOSPHORYLATED "SWITCH" IN BACTERIAL SIGNAL TRANSDUCTION | Descriptor: | NITROGEN REGULATION PROTEIN | Authors: | Kern, D, Volkman, B.F, Luginbuhl, P, Nohaile, M.J, Kustu, S, Wemmer, D.E. | Deposit date: | 1999-11-04 | Release date: | 2000-01-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of a transiently phosphorylated switch in bacterial signal transduction. Nature, 402, 1999
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1DP0
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![BU of 1dp0 by Molmil](/molmil-images/mine/1dp0) | E. COLI BETA-GALACTOSIDASE AT 1.7 ANGSTROM | Descriptor: | BETA-GALACTOSIDASE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | Deposit date: | 1999-12-22 | Release date: | 2001-02-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation. Protein Sci., 9, 2000
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8TO3
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![BU of 8to3 by Molmil](/molmil-images/mine/8to3) | EGFR(T790M/V948R) in complex with LN5461 | Descriptor: | 3-hydroxy-N-{(3P)-3-[(4P)-2-(methylsulfanyl)-5-{2-[4-(piperazin-1-yl)anilino]pyridin-4-yl}-1H-imidazol-4-yl]phenyl}-2-[(1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzamide, Epidermal growth factor receptor, MAGNESIUM ION, ... | Authors: | Chitnis, S.C, Pham, C.D, Heppner, D.E. | Deposit date: | 2023-08-02 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | EGFR(T790M/V948R) in complex with LN5461 To Be Published
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3LTG
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![BU of 3ltg by Molmil](/molmil-images/mine/3ltg) | |
8TO4
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![BU of 8to4 by Molmil](/molmil-images/mine/8to4) | EGFR(T790M/V948R) in complex with the allosteric inhibitor FRF-06-057 | Descriptor: | (2R)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, MAGNESIUM ION, ... | Authors: | Chitnis, S.P, Deng, M.Q, Pham, C.P, Heppner, D.E. | Deposit date: | 2023-08-02 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | EGFR(T790M/V948R) in complex with the allosteric inhibitor FRF-06-057 To Be Published
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1DC8
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![BU of 1dc8 by Molmil](/molmil-images/mine/1dc8) | STRUCTURE OF A TRANSIENTLY PHOSPHORYLATED "SWITCH" IN BACTERIAL SIGNAL TRANSDUCTION | Descriptor: | NITROGEN REGULATION PROTEIN | Authors: | Kern, D, Volkman, B.F, Luginbuhl, P, Nohaile, M.J, Kustu, S, Wemmer, D.E. | Deposit date: | 1999-11-04 | Release date: | 2000-01-05 | Last modified: | 2022-12-21 | Method: | SOLUTION NMR | Cite: | Structure of a transiently phosphorylated switch in bacterial signal transduction. Nature, 402, 1999
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8UCX
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![BU of 8ucx by Molmil](/molmil-images/mine/8ucx) | |
3SOD
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![BU of 3sod by Molmil](/molmil-images/mine/3sod) | CHANGES IN CRYSTALLOGRAPHIC STRUCTURE AND THERMOSTABILITY OF A CU,ZN SUPEROXIDE DISMUTASE MUTANT RESULTING FROM THE REMOVAL OF BURIED CYSTEINE | Descriptor: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | Authors: | Mcree, D.E, Redford, S.M, Getzoff, E.D, Lepock, J.R, Hallewell, R.A, Tainer, J.A. | Deposit date: | 1990-06-26 | Release date: | 1993-04-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine. J.Biol.Chem., 265, 1990
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1ASH
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![BU of 1ash by Molmil](/molmil-images/mine/1ash) | THE STRUCTURE OF ASCARIS HEMOGLOBIN DOMAIN I AT 2.2 ANGSTROMS RESOLUTION: MOLECULAR FEATURES OF OXYGEN AVIDITY | Descriptor: | HEMOGLOBIN (OXY), OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Yang, J, Mathews, F.S, Kloek, A.P, Goldberg, D.E. | Deposit date: | 1995-01-06 | Release date: | 1995-02-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The structure of Ascaris hemoglobin domain I at 2.2 A resolution: molecular features of oxygen avidity. Proc.Natl.Acad.Sci.USA, 92, 1995
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1CCG
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![BU of 1ccg by Molmil](/molmil-images/mine/1ccg) | CONSTRUCTION OF A BIS-AQUO HEME ENZYME AND REPLACEMENT WITH EXOGENOUS LIGAND | Descriptor: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mcree, D.E, Jensen, G.M, Fitzgerald, M.M, Siegel, H.A, Goodin, D.B. | Deposit date: | 1994-05-04 | Release date: | 1994-07-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Construction of a bisaquo heme enzyme and binding by exogenous ligands. Proc.Natl.Acad.Sci.USA, 91, 1994
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1CCE
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![BU of 1cce by Molmil](/molmil-images/mine/1cce) | CONSTRUCTION OF A BIS-AQUO HEME ENZYME AND REPLACEMENT WITH EXOGENOUS LIGAND | Descriptor: | CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mcree, D.E, Jensen, G.M, Fitzgerald, M.M, Siegel, H.A, Goodin, D.B. | Deposit date: | 1994-05-04 | Release date: | 1994-07-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Construction of a bisaquo heme enzyme and binding by exogenous ligands. Proc.Natl.Acad.Sci.USA, 91, 1994
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3LGK
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![BU of 3lgk by Molmil](/molmil-images/mine/3lgk) | D99N Epi-isozizaene synthase | Descriptor: | Epi-isozizaene synthase, SULFATE ION | Authors: | Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W. | Deposit date: | 2010-01-20 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.892 Å) | Cite: | Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates Biochemistry, 49, 2010
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8UWV
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![BU of 8uwv by Molmil](/molmil-images/mine/8uwv) | |
3LG5
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![BU of 3lg5 by Molmil](/molmil-images/mine/3lg5) | F198A Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation | Descriptor: | Epi-isozizaene synthase, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ... | Authors: | Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W. | Deposit date: | 2010-01-19 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.641 Å) | Cite: | Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates Biochemistry, 49, 2010
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6REN
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![BU of 6ren by Molmil](/molmil-images/mine/6ren) | Crystal structure of 3fPizza6-SH with Zn2+ | Descriptor: | 3fPizza6-SH, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2019-07-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Artificial beta-propeller protein-based hydrolases. Chem.Commun.(Camb.), 55, 2019
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6REH
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![BU of 6reh by Molmil](/molmil-images/mine/6reh) | Crystal structure of Pizza6-S with Cu2+ | Descriptor: | COPPER (II) ION, GLYCEROL, Pizza6-S, ... | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2019-07-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Artificial beta-propeller protein-based hydrolases. Chem.Commun.(Camb.), 55, 2019
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6REJ
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![BU of 6rej by Molmil](/molmil-images/mine/6rej) | Crystal structure of Pizza6-SH with Zn2+ | Descriptor: | Pizza6-SH, SULFATE ION, ZINC ION | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2019-07-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Artificial beta-propeller protein-based hydrolases. Chem.Commun.(Camb.), 55, 2019
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6REO
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![BU of 6reo by Molmil](/molmil-images/mine/6reo) | Crystal structure of 3fPizza6-SH with Sulphate ion | Descriptor: | 3fPizza6-SH, SULFATE ION | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Artificial beta-Propeller Protein-based Hydrolases To Be Published
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3LTF
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![BU of 3ltf by Molmil](/molmil-images/mine/3ltf) | Crystal Structure of the Drosophila Epidermal Growth Factor Receptor ectodomain in complex with Spitz | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ... | Authors: | Alvarado, D, Klein, D.E, Lemmon, M.A. | Deposit date: | 2010-02-15 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for negative cooperativity in growth factor binding to an EGF receptor. Cell(Cambridge,Mass.), 142, 2010
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