8TO3

EGFR(T790M/V948R) in complex with LN5461

Summary for 8TO3

• Entry DOI: 10.2210/pdb8to3/pdb
• Descriptor: Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: cancer, inhibitor, kinase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 152231.83

Authors

Chitnis, S.C.,Pham, C.D.,Heppner, D.E. (deposition date: 2023-08-02, release date: 2024-08-28)

• Primary citation: Chitnis, S.P.,Pham, C.D.,Heppner, D.E.; EGFR(T790M/V948R) in complex with LN5461; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.49 Å)