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PDB: 1157 results

3QHY
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Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases
Descriptor: Beta-lactamase, Beta-lactamase inhibitory protein II
Authors:Brown, N.G, Chow, D.C, Sankaran, B, Zwart, P, Prasad, B.V.V, Palzkill, T, Berkeley Structural Genomics Center (BSGC)
Deposit date:2011-01-26
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases.
J.Biol.Chem., 286, 2011
3QL3
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Re-refined coordinates for PDB entry 1RX2
Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2011-02-02
Release date:2011-04-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Science, 332, 2011
3Q44
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X-ray crystal structure of PfA-M1 bound to Bestatin derivative 16
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S, Greenbaum, D.C.
Deposit date:2010-12-22
Release date:2011-03-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the s1 pocket of the essential malaria m1 metalloaminopeptidase.
J.Med.Chem., 54, 2011
3QL0
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Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase
Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2011-02-02
Release date:2011-04-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Science, 332, 2011
3RTR
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A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases
Descriptor: Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION
Authors:Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A.
Deposit date:2011-05-03
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
3SDY
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Crystal Structure of Broadly Neutralizing Antibody CR8020 Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8020, Heavy Chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-06-09
Release date:2011-07-20
Last modified:2021-04-07
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A highly conserved neutralizing epitope on group 2 influenza A viruses.
Science, 333, 2011
3QHF
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Crystal Structure of Fab del2D1, a deletion variant of anti-influenza antibody 2D1
Descriptor: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-01-25
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.655 Å)
Cite:An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
3QI0
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BU of 3qi0 by Molmil
Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases
Descriptor: Beta-lactamase inhibitory protein II, SULFATE ION
Authors:Brown, N.G, Chow, D.C, Sankaran, B, Zwart, P, Prasad, B.V.V, Palzkill, T.
Deposit date:2011-01-26
Release date:2011-07-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases.
J.Biol.Chem., 286, 2011
3QHZ
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BU of 3qhz by Molmil
Crystal Structure of human anti-influenza Fab 2D1
Descriptor: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-01-26
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
3TC1
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Crystal Structure of Octaprenyl Pyrophosphate Synthase from Helicobacter pylori
Descriptor: MAGNESIUM ION, Octaprenyl Pyrophosphate Synthase
Authors:Zhang, J.Y, Zhang, X.L, Li, D.F, Zou, Q.M, Wang, D.C.
Deposit date:2011-08-08
Release date:2011-08-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Octaprenyl Pyrophosphate Synthase from Helicobacter pylori
To be Published
3Q43
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X-ray crystal structure of PfA-M1 bound to bestatin derivative 15
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S, Greenbaum, D.C.
Deposit date:2010-12-22
Release date:2011-03-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the s1 pocket of the essential malaria m1 metalloaminopeptidase.
J.Med.Chem., 54, 2011
3TDI
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yeast Cul1WHB-Dcn1P acetylated Ubc12N complex
Descriptor: Defective in cullin neddylation protein 1, NEDD8-conjugating enzyme UBC12
Authors:Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A.
Deposit date:2011-08-11
Release date:2011-10-12
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Science, 334, 2011
3TDZ
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N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-stapled acetylated Ubc12N complex
Descriptor: Cullin-1, DCN1-like protein 1, STAPLED PEPTIDE
Authors:Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A.
Deposit date:2011-08-11
Release date:2011-10-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Science, 334, 2011
3TDU
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BU of 3tdu by Molmil
N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-acetylated Ubc12N complex
Descriptor: Cullin-1, DCN1-like protein 1, NEDD8-conjugating enzyme Ubc12
Authors:Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A.
Deposit date:2011-08-11
Release date:2011-10-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Science, 334, 2011
3R2X
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BU of 3r2x by Molmil
Crystal structure of the de novo designed binding protein HB36.3 in complex the the 1918 influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HB36.3, designed hemagglutinin binding protein, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-03-14
Release date:2011-05-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.
Science, 332, 2011
3SXL
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BU of 3sxl by Molmil
SEX-LETHAL RNA RECOGNITION DOMAINS 1 AND 2 FROM DROSOPHILA MELANOGASTER
Descriptor: PROTEIN (SEX-LETHAL)
Authors:Crowder, S.M, Kanaar, R, Rio, D.C, Alber, T.C.
Deposit date:1999-04-04
Release date:1999-04-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Absence of interdomain contacts in the crystal structure of the RNA recognition motifs of Sex-lethal.
Proc.Natl.Acad.Sci.USA, 96, 1999
3TG0
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BU of 3tg0 by Molmil
E. coli alkaline phosphatase with bound inorganic phosphate
Descriptor: Alkaline phosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Bobyr, E, Lassila, J.K, Wiersma-Koch, H.I, Fenn, T.D, Lee, J.J, Nikolic-Hughes, I, Hodgson, K.O, Rees, D.C, Hedman, B, Herschlag, D.
Deposit date:2011-08-16
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography.
J.Mol.Biol., 415, 2012
3SLK
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BU of 3slk by Molmil
Structure of ketoreductase and enoylreductase didomain from modular polyketide synthase
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polyketide synthase extender module 2, SULFATE ION
Authors:Zheng, J, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2011-06-24
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Divergence of multimodular polyketide synthases revealed by a didomain structure.
Nat.Chem.Biol., 8, 2012
3U1N
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BU of 3u1n by Molmil
Structure of the catalytic core of human SAMHD1
Descriptor: PHOSPHATE ION, SAM domain and HD domain-containing protein 1, ZINC ION
Authors:Goldstone, D.C, Ennis-Adeniran, V, Walker, P.A, Haire, L.F, Webb, M, Taylor, I.A.
Deposit date:2011-09-30
Release date:2011-11-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
Nature, 480, 2011
3TUI
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BU of 3tui by Molmil
Inward facing conformations of the MetNI methionine ABC transporter: CY5 native crystal form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-methionine transport system permease protein metI, Methionine import ATP-binding protein MetN
Authors:Johnson, E, Nguyen, P.T, Rees, D.C.
Deposit date:2011-09-16
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inward facing conformations of the MetNI methionine ABC transporter: Implications for the mechanism of transinhibition.
Protein Sci., 21, 2012
3TUJ
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BU of 3tuj by Molmil
Inward facing conformations of the MetNI methionine ABC transporter: DM crystal form
Descriptor: D-methionine transport system permease protein metI, Methionine import ATP-binding protein MetN
Authors:Johnson, E, Nguyen, P, Rees, D.C.
Deposit date:2011-09-16
Release date:2011-11-30
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Inward facing conformations of the MetNI methionine ABC transporter: Implications for the mechanism of transinhibition.
Protein Sci., 21, 2012
3TUZ
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BU of 3tuz by Molmil
Inward facing conformations of the MetNI methionine ABC transporter: CY5 SeMet soak crystal form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-methionine transport system permease protein metI, Methionine import ATP-binding protein MetN, ...
Authors:Johnson, E, Nguyen, P, Rees, D.C.
Deposit date:2011-09-19
Release date:2011-11-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Inward facing conformations of the MetNI methionine ABC transporter: Implications for the mechanism of transinhibition.
Protein Sci., 21, 2012
3TMM
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BU of 3tmm by Molmil
TFAM imposes a U-turn on mitochondrial DNA
Descriptor: DNA (28-MER), Transcription factor A, mitochondrial
Authors:Ngo, H.B, Kaiser, J.T, Chan, D.C.
Deposit date:2011-08-31
Release date:2011-11-09
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.5001 Å)
Cite:The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA.
Nat.Struct.Mol.Biol., 18, 2011
3LFK
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A reported archaeal mechanosensitive channel is a structural homolog of MarR-like transcriptional regulators
Descriptor: CITRIC ACID, MarR Like Protein, TVG0766549, ...
Authors:Liu, Z, Walton, T.A, Rees, D.C.
Deposit date:2010-01-17
Release date:2010-04-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A reported archaeal mechanosensitive channel is a structural homolog of MarR-like transcriptional regulators.
Protein Sci., 19, 2010
3LZF
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BU of 3lzf by Molmil
Crystal Structure of Fab 2D1 in Complex with the 1918 Influenza Virus Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2D1 Fab, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2010-03-01
Release date:2010-04-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010

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數據於2024-07-10公開中

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