3U1N
Structure of the catalytic core of human SAMHD1
Summary for 3U1N
| Entry DOI | 10.2210/pdb3u1n/pdb |
| Descriptor | SAM domain and HD domain-containing protein 1, PHOSPHATE ION, ZINC ION, ... (4 entities in total) |
| Functional Keywords | hd-domain, deoxynucleotide triphosphohydrolase, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus : Q9Y3Z3 |
| Total number of polymer chains | 4 |
| Total formula weight | 246727.97 |
| Authors | Goldstone, D.C.,Ennis-Adeniran, V.,Walker, P.A.,Haire, L.F.,Webb, M.,Taylor, I.A. (deposition date: 2011-09-30, release date: 2011-11-16, Last modification date: 2018-01-24) |
| Primary citation | Goldstone, D.C.,Ennis-Adeniran, V.,Hedden, J.J.,Groom, H.C.,Rice, G.I.,Christodoulou, E.,Walker, P.A.,Kelly, G.,Haire, L.F.,Yap, M.W.,de Carvalho, L.P.,Stoye, J.P.,Crow, Y.J.,Taylor, I.A.,Webb, M. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase Nature, 480:379-382, 2011 Cited by PubMed: 22056990DOI: 10.1038/nature10623 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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