3SLK

Structure of ketoreductase and enoylreductase didomain from modular polyketide synthase

Summary for 3SLK

Entry DOI	10.2210/pdb3slk/pdb
Descriptor	Polyketide synthase extender module 2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION (3 entities in total)
Functional Keywords	rossmann fold, nadph, oxidoreductase
Biological source	Saccharopolyspora spinosa
Total number of polymer chains	2
Total formula weight	170118.98
Authors	Zheng, J.,Gay, D.C.,Keatinge-Clay, A.T. (deposition date: 2011-06-24, release date: 2012-05-30, Last modification date: 2024-02-28)
Primary citation	Zheng, J.,Gay, D.C.,Demeler, B.,White, M.A.,Keatinge-Clay, A.T. Divergence of multimodular polyketide synthases revealed by a didomain structure. Nat.Chem.Biol., 8:615-621, 2012 Cited by PubMed: 22634636 DOI: 10.1038/nchembio.964 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation