8ENL
 
 | | CryoEM structure of the high pH turnover-inactivated nitrogenase MoFe-protein | | 分子名称: | CHAPSO, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | 著者 | Warmack, R.A, Maggiolo, A.O, Rees, D.C. | | 登録日 | 2022-09-30 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.37 Å) | | 主引用文献 | Structural consequences of turnover-induced homocitrate loss in nitrogenase.
Nat Commun, 14, 2023
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8ENN
 | | Homocitrate-deficient nitrogenase MoFe-protein from Azotobacter vinelandii nifV knockout | | 分子名称: | CHAPSO, CITRIC ACID, FE (III) ION, ... | | 著者 | Warmack, R.A, Maggiolo, A.O, Rees, D.C. | | 登録日 | 2022-09-30 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | | 主引用文献 | Structural consequences of turnover-induced homocitrate loss in nitrogenase.
Nat Commun, 14, 2023
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8ENM
 | | CryoEM structure of the high pH nitrogenase MoFe-protein under non-turnover conditions | | 分子名称: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | 著者 | Warmack, R.A, Maggiolo, A.O, Rees, D.C. | | 登録日 | 2022-09-30 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.14 Å) | | 主引用文献 | Structural consequences of turnover-induced homocitrate loss in nitrogenase.
Nat Commun, 14, 2023
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8ENO
 | | Homocitrate-deficient nitrogenase MoFe-protein from A. vinelandii nifV knockout in complex with NafT | | 分子名称: | CHAPSO, CITRIC ACID, FE (III) ION, ... | | 著者 | Warmack, R.A, Maggiolo, A.O, Rees, D.C. | | 登録日 | 2022-09-30 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Structural consequences of turnover-induced homocitrate loss in nitrogenase.
Nat Commun, 14, 2023
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4Z7M
 | | Novel Inhibitors of Bacterial Methionine Aminopeptidase with Broad-Spectrum Biochemical Activity | | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase, N~2~-[(3,5-difluorophenyl)acetyl]-N-[(3S,7R)-1-methyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-L-alaninamide | | 著者 | Rose, J.A, Lahiri, S.D, McKinney, D.C, Albert, R, Morningstar, M, Shapiro, A.B, Fisher, S.F, Fleming, P.R. | | 登録日 | 2015-04-07 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Novel Inhibitors of Bacterial Methionine Aminopeptidase with Broad-Spectrum Biochemical Activity
To be Published
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4ZTC
 | | PglE Aminotransferase in complex with External Aldimine, Mutant K184A | | 分子名称: | Aminotransferase homolog, [(2R,3R,4R,5S,6R)-3-acetamido-6-methyl-5-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-4-oxidanyl-oxan-2-yl] [[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | | 著者 | Riegert, A.S, Thoden, J.B, Young, N.M, Watson, D.C, Holden, H.M. | | 登録日 | 2015-05-14 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the external aldimine form of PglE, an aminotransferase required for N,N'-diacetylbacillosamine biosynthesis.
Protein Sci., 24, 2015
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8EV5
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4ZRZ
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8F22
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8FEF
 | | Structure of Mce1 transporter from Mycobacterium smegmatis (Map0) | | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
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8FED
 | | Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1) | | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
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8FEE
 | | Structure of Mce1 transporter from Mycobacterium smegmatis in the absence of LucB (Map2) | | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
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8FQ7
 | | Nanobody with WIW inserted in CDR3 loop to Inhibit Growth of Alzheimer's Tau fibrils | | 分子名称: | GLYCEROL, Nanobody with WIW insert in CDR3 loop to target tau fibrils | | 著者 | Abskharon, R, Sawaya, M.R, Cascio, D.C, Eisenberg, D.S. | | 登録日 | 2023-01-05 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EV4
 | | NlpC B3 - Trichomonas Vaginalis | | 分子名称: | Clan CA, family C40, NlpC/P60 superfamily cysteine peptidase | | 著者 | Barnett, M.J, Goldstone, D.C. | | 登録日 | 2022-10-19 | | 公開日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli.
Plos Pathog., 19, 2023
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8FUH
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8FVV
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8FXD
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5A0O
 | | adhiron raised against p300 | | 分子名称: | ADHIRON | | 著者 | Kyle, H.F, Wickson, K.F, Stott, J, Burslem, G.M, Breeze, A.L, Tiede, C, Tomlinson, D.C, Warriner, S.L, Nelson, A, Wilson, A.J, Edwards, T.A. | | 登録日 | 2015-04-21 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Exploration of the Hif-1Alpha.P300 Interface Using Peptide and Adhiron Phage Display Technologies
Mol.Biosyst., 11, 2015
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5BNR
 | | E. coli Fabh with small molecule inhibitor 2 | | 分子名称: | 1-{5-[2-fluoro-5-(hydroxymethyl)phenyl]pyridin-2-yl}piperidine-4-carboxylic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 3 | | 著者 | Kazmirski, S.L, McKinney, D.C. | | 登録日 | 2015-05-26 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping.
Acs Infect Dis., 2, 2016
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5AO5
 | | Endo180 D1-4, monoclinic form | | 分子名称: | C-TYPE MANNOSE RECEPTOR 2, SODIUM ION, SULFATE ION | | 著者 | Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E. | | 登録日 | 2015-09-09 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Structure, 23, 2015
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5BNM
 | | E. coli FabH with Small Molecule Inhibitor 1 | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, N-{[3'-(hydroxymethyl)biphenyl-4-yl]methyl}benzenesulfonamide, SULFATE ION, ... | | 著者 | Kazmirski, S.L, McKinney, D.C. | | 登録日 | 2015-05-26 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping.
Acs Infect Dis., 2, 2016
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5AO6
 | | Endo180 D1-4, trigonal form | | 分子名称: | C-TYPE MANNOSE RECEPTOR 2 | | 著者 | Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E. | | 登録日 | 2015-09-09 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | | 主引用文献 | Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Structure, 23, 2015
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5BQS
 | | S. Pneumoniae Fabh with small molecule inhibitor 4 | | 分子名称: | 1-{5-[2-chloro-5-(hydroxymethyl)phenyl]pyridin-2-yl}piperidine-4-carboxylic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 3, SODIUM ION | | 著者 | Kazmirski, S.L, McKinney, D.C. | | 登録日 | 2015-05-29 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping.
Acs Infect Dis., 2, 2016
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5BNS
 | | E. coli Fabh with small molecule inhibitor 2 | | 分子名称: | 1-{5-[2-fluoro-5-(hydroxymethyl)phenyl]pyridin-2-yl}-N-(quinolin-6-ylmethyl)piperidine-4-carboxamide, 3-oxoacyl-[acyl-carrier-protein] synthase 3 | | 著者 | Kazmirski, S.L, McKinney, D.C. | | 登録日 | 2015-05-26 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping.
Acs Infect Dis., 2, 2016
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6OQP
 | | U-AITx-Ate1 | | 分子名称: | SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE | | 著者 | Elnahriry, K.A, Wai, D.C.C, Norton, R.S. | | 登録日 | 2019-04-28 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa.
Toxicon, 168, 2019
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