8AEX
| Lipidic alpha-synuclein fibril - polymorph L3A | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-07-14 | Release date: | 2022-10-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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8ADS
| Lipidic alpha-synuclein fibril - polymorph L2B | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-07-11 | Release date: | 2022-10-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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8ADV
| Lipidic alpha-synuclein fibril - polymorph L1B | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-07-11 | Release date: | 2022-10-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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5NUP
| Structural basis for maintenance of bacterial outer membrane lipid asymmetry | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ABC transporter permease, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B. | Deposit date: | 2017-05-01 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for maintenance of bacterial outer membrane lipid asymmetry. Nat Microbiol, 2, 2017
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5O71
| Crystal structure of human USP25 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 25 | Authors: | Reverter, D, Liu, B. | Deposit date: | 2017-06-07 | Release date: | 2018-06-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.283 Å) | Cite: | A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25. Nat Commun, 9, 2018
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2KE8
| NMR solution structure of metal-modified DNA | Descriptor: | DNA (5'-D(*TP*TP*AP*AP*TP*TP*TP*(D33)P*(D33)P*(D33)P*AP*AP*AP*TP*TP*AP*A)-3'), SILVER ION | Authors: | Johannsen, S, Duepre, N, Boehme, D, Mueller, J, Sigel, R.K.O. | Deposit date: | 2009-01-27 | Release date: | 2010-02-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of a DNA double helix with consecutive metal-mediated base pairs. Nat.Chem., 2, 2010
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4PQ8
| Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR465 | Descriptor: | CHLORIDE ION, DESIGNED PROTEIN OR465 | Authors: | Vorobiev, S, Parmeggiani, F, Seetharaman, J, Janjua, H, Xiao, R, Maglaqui, M, Park, K, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2014-02-28 | Release date: | 2014-03-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.833 Å) | Cite: | Crystal Structure of Engineered Protein OR465. To be Published
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5O7O
| The crystal structure of DfoC, the desferrioxamine biosynthetic pathway acetyltransferase/Non-Ribosomal Peptide Synthetase (NRPS)-Independent Siderophore (NIS) from the fire blight disease pathogen Erwinia amylovora | Descriptor: | Desferrioxamine siderophore biosynthesis protein dfoC | Authors: | Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S. | Deposit date: | 2017-06-09 | Release date: | 2018-02-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora. J. Struct. Biol., 202, 2018
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5NWY
| 2.9 A cryo-EM structure of VemP-stalled ribosome-nascent chain complex | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Su, T, Cheng, J, Sohmen, D, Hedman, R, Berninghausen, O, von Heijne, G, Wilson, D.N, Beckmann, R. | Deposit date: | 2017-05-08 | Release date: | 2017-07-19 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling. Elife, 6, 2017
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5OD1
| Structure of the engineered metalloesterase MID1sc10 complexed with a phosphonate transition state analogue | Descriptor: | GLYCEROL, MID1sc10, ZINC ION, ... | Authors: | Mittl, P.R.E, Studer, S, Hansen, D.A, Hilvert, D. | Deposit date: | 2017-07-04 | Release date: | 2018-12-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Evolution of a highly active and enantiospecific metalloenzyme from short peptides. Science, 362, 2018
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7BOH
| Complete Bacterial 30S ribosomal subunit assembly complex state E (+RbfA)(Consensus Refinement) | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | Deposit date: | 2021-01-25 | Release date: | 2021-12-08 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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5OD8
| Crystal structure of the RA-associated mAb B2 (Fab fragment) | Descriptor: | B2 Fab fragment - Light chain, B2 Fab fragment - heavy chain | Authors: | Dobritzsch, D, Ge, C, Holmdahl, R, Amara, K, Malmstrom, V. | Deposit date: | 2017-07-05 | Release date: | 2018-07-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies. Arthritis Rheumatol, 71, 2019
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7BOE
| Bacterial 30S ribosomal subunit assembly complex state M (Consensus refinement) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.R. | Deposit date: | 2021-01-25 | Release date: | 2021-12-08 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7BKX
| Diploptera punctata inspired lipocalin-like Milk protein expressed in Saccharomyces cerevisiae | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Banerjee, S, Kanagavijayan, D, Subramanian, R, Santhakumari, P.R, Chavas, L.M.G, Ramaswamy, S. | Deposit date: | 2021-01-17 | Release date: | 2021-12-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of recombinantly expressed cockroach Lili-Mip protein in glycosylated and deglycosylated forms. Biochim Biophys Acta Gen Subj, 1866, 2022
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4PSJ
| Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium (NESG) Target OR464. | Descriptor: | OR464 | Authors: | Vorobiev, S, Parmeggiani, F, Seetharaman, J, Huang, P.-S, Janjua, H, Xiao, R, Maglaqui, M, Park, K, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2014-03-07 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.992 Å) | Cite: | Crystal Structure of Engineered Protein OR464. To be Published
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5OD7
| Hsp90 inhibitor desolvation as a rationale to steer on-rates and impact residence time | Descriptor: | Heat shock protein HSP 90-alpha, [2-azanyl-6-[2-(4-methylpiperazin-1-yl)sulfonylphenyl]quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone | Authors: | Schuetz, D.A, Richter, L, Amaral, M, Grandits, M, Musil, D, Graedler, U, Buchstaller, H.-P, Eggenweiler, H.-M, Frech, M, Ecker, G.F, Lehmann, M. | Deposit date: | 2017-07-04 | Release date: | 2018-11-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors. J.Med.Chem., 61, 2018
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5NUQ
| Structural basis for maintenance of bacterial outer membrane lipid asymmetry | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Outer membrane protein F, Probable phospholipid-binding lipoprotein mlaA | Authors: | Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B. | Deposit date: | 2017-05-01 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for maintenance of bacterial outer membrane lipid asymmetry. Nat Microbiol, 2, 2017
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7BAG
| C3b in complex with CP40 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETAMIDE, AMINO GROUP, ... | Authors: | Lamers, C, Xue, X, Smiesko, M, van Son, H, Wagner, B, Sfyroera, G, Gros, P, Lambris, J, Ricklin, D. | Deposit date: | 2020-12-15 | Release date: | 2022-01-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors. Nat Commun, 13, 2022
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5OEG
| Molecular tweezers modulate 14-3-3 protein-protein interactions | Descriptor: | (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION | Authors: | Bier, D, Ottmann, C. | Deposit date: | 2017-07-07 | Release date: | 2017-07-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Molecular tweezers modulate 14-3-3 protein-protein interactions. Nat Chem, 5, 2013
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4HCW
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5NUO
| Structural basis for maintenance of bacterial outer membrane lipid asymmetry | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ABC transporter permease, Outer membrane protein F, ... | Authors: | Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B. | Deposit date: | 2017-05-01 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for maintenance of bacterial outer membrane lipid asymmetry. Nat Microbiol, 2, 2017
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5NVM
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5NUR
| Structural basis for maintenance of bacterial outer membrane lipid asymmetry | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(3-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, ... | Authors: | Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B. | Deposit date: | 2017-05-01 | Release date: | 2017-10-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Structural basis for maintenance of bacterial outer membrane lipid asymmetry. Nat Microbiol, 2, 2017
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5NVN
| Crystal structure of the human 4EHP-4E-BP1 complex | Descriptor: | Eukaryotic translation initiation factor 4E type 2, Eukaryotic translation initiation factor 4E-binding protein 1, FORMIC ACID | Authors: | Peter, D, Sandmeir, F, Valkov, E. | Deposit date: | 2017-05-04 | Release date: | 2017-07-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes Dev., 31, 2017
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5O4P
| Crystal structure of AMPylated GRP78 | Descriptor: | 78 kDa glucose-regulated protein, ADENOSINE MONOPHOSPHATE, SULFATE ION | Authors: | Yan, Y, Chen, R, Ron, D, Read, R. | Deposit date: | 2017-05-30 | Release date: | 2017-11-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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