5OD1
Structure of the engineered metalloesterase MID1sc10 complexed with a phosphonate transition state analogue
Summary for 5OD1
Entry DOI | 10.2210/pdb5od1/pdb |
Descriptor | MID1sc10, ZINC ION, [2-oxidanylidene-7-[oxidanyl-[(1~{S})-1-phenylethyl]phosphoryl]oxy-chromen-4-yl]methanesulfonic acid, ... (5 entities in total) |
Functional Keywords | directed evolution, engineered metalloenzyme, de novo protein-hydrolase, de novo protein-hydrolase complex, de novo protein/hydrolase |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 11450.94 |
Authors | Mittl, P.R.E.,Studer, S.,Hansen, D.A.,Hilvert, D. (deposition date: 2017-07-04, release date: 2018-12-12, Last modification date: 2024-05-08) |
Primary citation | Studer, S.,Hansen, D.A.,Pianowski, Z.L.,Mittl, P.R.E.,Debon, A.,Guffy, S.L.,Der, B.S.,Kuhlman, B.,Hilvert, D. Evolution of a highly active and enantiospecific metalloenzyme from short peptides. Science, 362:1285-1288, 2018 Cited by PubMed: 30545884DOI: 10.1126/science.aau3744 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.34 Å) |
Structure validation
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