1YOW
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![BU of 1yow by Molmil](/molmil-images/mine/1yow) | human Steroidogenic Factor 1 LBD with bound Co-factor Peptide | Descriptor: | PHOSPHATIDYL ETHANOL, Steroidogenic factor 1, TIF2 peptide | Authors: | Krylova, I.N, Sablin, E.P, Xu, R.X, Waitt, G.M, Juzumiene, D, Williams, J.D, Ingraham, H.A, Willson, T.M, Williams, S.P, Montana, V, Madauss, K.P, Moore, J, Bynum, J.M, Lebedeva, L, MacKay, J.A, Suzawa, M, Guy, R.K, Thornton, J.W. | Deposit date: | 2005-01-28 | Release date: | 2005-05-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 Cell(Cambridge,Mass.), 120, 2005
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1YSB
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![BU of 1ysb by Molmil](/molmil-images/mine/1ysb) | Yeast Cytosine Deaminase Triple Mutant | Descriptor: | CALCIUM ION, Cytosine deaminase, ZINC ION | Authors: | Korkegian, A, Black, M.E, Baker, D, Stoddard, B.L. | Deposit date: | 2005-02-08 | Release date: | 2005-05-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Computational thermostabilization of an enzyme. Science, 308, 2005
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1YU5
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![BU of 1yu5 by Molmil](/molmil-images/mine/1yu5) | Crystal Structure of the Headpiece Domain of Chicken Villin | Descriptor: | Villin | Authors: | Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J. | Deposit date: | 2005-02-11 | Release date: | 2005-09-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution crystal structures of villin headpiece and mutants with reduced f-actin binding activity. Biochemistry, 44, 2005
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4U9P
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![BU of 4u9p by Molmil](/molmil-images/mine/4u9p) | Structure of the methanofuran/methanopterin biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii | Descriptor: | GLYCEROL, UPF0264 protein MJ1099 | Authors: | Bobik, T.A, Morales, E, Shin, A, Cascio, D, Sawaya, M.R, Arbing, M, Rasche, M.E. | Deposit date: | 2014-08-06 | Release date: | 2014-11-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the methanofuran/methanopterin-biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii. Acta Crystallogr.,Sect.F, 70, 2014
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1YNQ
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![BU of 1ynq by Molmil](/molmil-images/mine/1ynq) | aldo-keto reductase AKR11C1 from Bacillus halodurans (holo form) | Descriptor: | GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, ... | Authors: | Marquardt, T, Kostrewa, D, Winkler, F.K, Li, X.D. | Deposit date: | 2005-01-25 | Release date: | 2005-12-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase J.Mol.Biol., 354, 2005
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6EIG
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![BU of 6eig by Molmil](/molmil-images/mine/6eig) | Crystal structure of N24Q/C128T mutant of Channelrhodopsin 2 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 2, EICOSANE, ... | Authors: | Kovalev, K, Borshchevskiy, V, Volkov, O, Polovinkin, V, Marin, E, Balandin, T, Astashkin, R, Bamann, C, Bueldt, G, Willlbold, D, Popov, A, Bamberg, E, Gordeliy, V. | Deposit date: | 2017-09-19 | Release date: | 2017-12-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into ion conduction by channelrhodopsin 2. Science, 358, 2017
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1YU8
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![BU of 1yu8 by Molmil](/molmil-images/mine/1yu8) | Crystal Structure of the R37A Mutant of Villin Headpiece | Descriptor: | Villin | Authors: | Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J. | Deposit date: | 2005-02-12 | Release date: | 2005-09-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity. Biochemistry, 44, 2005
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1YQJ
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![BU of 1yqj by Molmil](/molmil-images/mine/1yqj) | Crystal Structure of p38 Alpha in Complex with a Selective Pyridazine Inhibitor | Descriptor: | 6((S)-3-BENZYLPIPERAZIN-1-YL)-3-(NAPHTHALEN-2-YL)-4-(PYRIDIN-4-YL)PYRAZINE, Mitogen-activated protein kinase 14, SULFATE ION | Authors: | Tamayo, N, Liao, H, Goldberg, M, Syed, R, Li, V, Powers, D, Tudor, Y, Yu, V, Wong, M.L, Henkle, B, Middelton, S, Harvey, T, Jang, G, Hungate, R, Dominguez, C. | Deposit date: | 2005-02-01 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase. Bioorg.Med.Chem.Lett., 15, 2005
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1YR3
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![BU of 1yr3 by Molmil](/molmil-images/mine/1yr3) | Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene | Descriptor: | SULFATE ION, XANTHINE, Xanthosine phosphorylase | Authors: | Dandanell, G, Szczepanowski, R.H, Kierdaszuk, B, Shugar, D, Bochtler, M. | Deposit date: | 2005-02-03 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene J.Mol.Biol., 348, 2005
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7A0N
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![BU of 7a0n by Molmil](/molmil-images/mine/7a0n) | Structure of TSC1 NTD and linker domain | Descriptor: | Uncharacterized protein,Uncharacterized protein | Authors: | Fitzian, K, Kuemmel, D. | Deposit date: | 2020-08-10 | Release date: | 2021-05-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Mol.Cell, 81, 2021
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1YO0
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![BU of 1yo0 by Molmil](/molmil-images/mine/1yo0) | Proton Transfer from His200 in Human Carbonic Anhydrase II | Descriptor: | CHLORIDE ION, Carbonic anhydrase II, ZINC ION | Authors: | Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N. | Deposit date: | 2005-01-26 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Proton transfer in a Thr200His mutant of human carbonic anhydrase II Proteins, 61, 2005
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4U92
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![BU of 4u92 by Molmil](/molmil-images/mine/4u92) | Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad | Descriptor: | BARIUM ION, DNA (5'-D(*CP*CP*AP*KP*GP*CP*GP*TP*GP*G)-3'), MAGNESIUM ION | Authors: | Paukstelis, P.J, Zhang, D, Huang, T, Lukeman, P. | Deposit date: | 2014-08-05 | Release date: | 2014-11-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad. Nucleic Acids Res., 42, 2014
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7A0M
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![BU of 7a0m by Molmil](/molmil-images/mine/7a0m) | TSC1 N-terminal domain | Descriptor: | SULFATE ION, TSC1 N-terminal domain | Authors: | Zech, R, Kiontke, S, Kuemmel, D. | Deposit date: | 2020-08-10 | Release date: | 2021-05-26 | Last modified: | 2021-07-14 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Mol.Cell, 81, 2021
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7A4J
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![BU of 7a4j by Molmil](/molmil-images/mine/7a4j) | Aquifex aeolicus lumazine synthase-derived nucleocapsid variant NC-4 | Descriptor: | Antitermination protein N,6,7-dimethyl-8-ribityllumazine synthase,6,7-dimethyl-8-ribityllumazine synthase | Authors: | Tetter, S, Hilvert, D. | Deposit date: | 2020-08-19 | Release date: | 2021-06-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein. Science, 372, 2021
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1YQU
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![BU of 1yqu by Molmil](/molmil-images/mine/1yqu) | Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene | Descriptor: | GUANINE, PHOSPHATE ION, Xanthosine phosphorylase | Authors: | Dandanell, G, Szczepanowski, R.H, Kierdaszuk, B, Shugar, D, Bochtler, M. | Deposit date: | 2005-02-02 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene J.Mol.Biol., 348, 2005
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1YNT
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![BU of 1ynt by Molmil](/molmil-images/mine/1ynt) | Structure of the monomeric form of T. gondii SAG1 surface antigen bound to a human Fab | Descriptor: | 4F11E12 Fab variable heavy chain region, 4F11E12 Fab variable light chain region, CADMIUM ION, ... | Authors: | Graille, M, Stura, E.A, Bossus, M, Muller, B.H, Letourneur, O, Battail-Poirot, N, Sibai, G, Rolland, D, Le Du, M.H, Ducancel, F. | Deposit date: | 2005-01-25 | Release date: | 2005-12-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response J.Mol.Biol., 354, 2005
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2PBN
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![BU of 2pbn by Molmil](/molmil-images/mine/2pbn) | Crystal structure of the human tyrosine receptor phosphate gamma | Descriptor: | Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Reyes, C, Pelletier, L, Jin, X, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-03-28 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
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1YSQ
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![BU of 1ysq by Molmil](/molmil-images/mine/1ysq) | The crystal structure of transcriptional regulator YaiJ | Descriptor: | HTH-type transcriptional regulator yiaJ, PHOSPHATE ION | Authors: | Bochkarev, A, Lunin, V.V, Ezersky, A, Evdokimova, E, Skarina, T, Xu, X, Borek, D, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-02-08 | Release date: | 2005-03-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural study of effector binding specificity in IclR transcriptional regulators To be Published
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1YTR
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![BU of 1ytr by Molmil](/molmil-images/mine/1ytr) | NMR structure of plantaricin a in dpc micelles, 20 structures | Descriptor: | Bacteriocin plantaricin A | Authors: | Kristiansen, P.E, Fimland, G, Mantzilas, D, Nissen-Meyer, J. | Deposit date: | 2005-02-11 | Release date: | 2005-05-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure and mode of action of the membrane-permeabilizing antimicrobial peptide pheromone plantaricin A J.Biol.Chem., 280, 2005
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4U2W
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![BU of 4u2w by Molmil](/molmil-images/mine/4u2w) | Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin | Descriptor: | 1,2-ETHANEDIOL, Bowman-Birk trypsin inhibitor, CALCIUM ION, ... | Authors: | Grudnik, P, Golik, P, Malicki, S, Debowski, D, Legowska, A, Rolka, K, Dubin, G. | Deposit date: | 2014-07-18 | Release date: | 2015-01-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin. Proteins, 83, 2015
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1YMQ
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![BU of 1ymq by Molmil](/molmil-images/mine/1ymq) | |
1YOK
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![BU of 1yok by Molmil](/molmil-images/mine/1yok) | crystal structure of human LRH-1 bound with TIF-2 peptide and phosphatidylglycerol | Descriptor: | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2 | Authors: | Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, MacKay, J.A, Juzumiene, D, Bynum, J.M, Madauss, K, Montana, V, Lebedeva, L, Suzawa, M, Williams, J.D, Williams, S.P, Guy, R.K, Thornton, J.W, Fletterick, R.J, Willson, T.M, Ingraham, H.A. | Deposit date: | 2005-01-27 | Release date: | 2005-07-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell(Cambridge,Mass.), 120, 2005
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4U65
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![BU of 4u65 by Molmil](/molmil-images/mine/4u65) | Structure of the periplasmic output domain of the Legionella pneumophila LapD ortholog CdgS9 in complex with Pseudomonas fluorescens LapG | Descriptor: | CALCIUM ION, Putative cystine protease, Two component histidine kinase, ... | Authors: | Chatterjee, D, Cooley, R.B, Boyd, C.D, Mehl, R.A, O'Toole, G.A, Sondermann, H.S. | Deposit date: | 2014-07-27 | Release date: | 2014-08-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanistic insight into the conserved allosteric regulation of periplasmic proteolysis by the signaling molecule cyclic-di-GMP. Elife, 3, 2014
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2AF5
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![BU of 2af5 by Molmil](/molmil-images/mine/2af5) | 2.5A X-ray Structure of Engineered OspA protein | Descriptor: | Engineered Outer Surface Protein A (OspA) with the inserted two beta-hairpins | Authors: | Makabe, K, Mcelheny, D, Tereshko, V, Hilyard, A, Koide, A, Koide, S. | Deposit date: | 2005-07-25 | Release date: | 2006-08-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Atomic structures of peptide self-assembly mimics. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2AFI
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![BU of 2afi by Molmil](/molmil-images/mine/2afi) | Crystal Structure of MgADP bound Av2-Av1 Complex | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Tezcan, F.A, Kaiser, J.T, Mustafi, D, Walton, M.Y, Howard, J.B, Rees, D.C. | Deposit date: | 2005-07-25 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Nitrogenase Complexes: Multiple Docking Sites for a Nucleotide Switch Protein Science, 309, 2005
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