7A0M
TSC1 N-terminal domain
Summary for 7A0M
Entry DOI | 10.2210/pdb7a0m/pdb |
Descriptor | TSC1 N-terminal domain, SULFATE ION (3 entities in total) |
Functional Keywords | tsc, gap, gtpase signaling, signaling protein |
Biological source | Chaetomium thermophilum |
Total number of polymer chains | 4 |
Total formula weight | 193076.65 |
Authors | Zech, R.,Kiontke, S.,Kuemmel, D. (deposition date: 2020-08-10, release date: 2021-05-26, Last modification date: 2021-07-14) |
Primary citation | Fitzian, K.,Bruckner, A.,Brohee, L.,Zech, R.,Antoni, C.,Kiontke, S.,Gasper, R.,Linard Matos, A.L.,Beel, S.,Wilhelm, S.,Gerke, V.,Ungermann, C.,Nellist, M.,Raunser, S.,Demetriades, C.,Oeckinghaus, A.,Kummel, D. TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Mol.Cell, 81:2705-, 2021 Cited by PubMed: 33974911DOI: 10.1016/j.molcel.2021.04.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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