2K49
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![BU of 2k49 by Molmil](/molmil-images/mine/2k49) | Solution NMR structure of UPF0339 protein SO3888 from Shewanella oneidensis. Northeast Structural Genomics Consortium target SoR190 | 分子名称: | UPF0339 protein SO_3888 | 著者 | Tang, Y, Wang, D, Nwosu, C, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-05-31 | 公開日 | 2008-07-08 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of UPF0339 protein SO3888 from Shewanella oneidensis. To be Published
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2JZA
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![BU of 2jza by Molmil](/molmil-images/mine/2jza) | Solution NMR structure of nitrite reductase [NAD(P)H] small subunit from Erwinia carotovora. Northeast Structural Genomics Consortium target EwR120 | 分子名称: | Nitrite reductase [NAD(P)H] small subunit | 著者 | Sathyamoorthy, B, Eletsky, A, Wang, D, Stokes, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-12-31 | 公開日 | 2008-01-22 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of nitrite reductase [NAD(P)H] small subunit from Erwinia carotovora. To be Published
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3SB9
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![BU of 3sb9 by Molmil](/molmil-images/mine/3sb9) | Cu-mediated Dimer of T4 Lysozyme R76H/R80H by Synthetic Symmetrization | 分子名称: | COPPER (II) ION, FORMIC ACID, Lysozyme | 著者 | Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-03 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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2JZT
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![BU of 2jzt by Molmil](/molmil-images/mine/2jzt) | Solution NMR structure of Q8ZP25_SALTY from Salmonella typhimurium. Northeast Structural Genomics Consortium target StR70 | 分子名称: | Putative thiol-disulfide isomerase and thioredoxin | 著者 | Parish, D, Liu, G, Shen, Y, Ho, C, Cunningham, K, Xiao, R, Swapna, G.V.T, Acton, T, Bansal, S, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-01-16 | 公開日 | 2008-02-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Protein chaperones Q8ZP25_SALTY from Salmonella typhimurium and HYAE_ECOLI from Escherichia coli exhibit thioredoxin-like structures despite lack of canonical thioredoxin active site sequence motif. J.STRUCT.FUNCT.GENOM., 9, 2008
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3ZL1
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![BU of 3zl1 by Molmil](/molmil-images/mine/3zl1) | A thiazolyl-mannoside bound to FimH, monoclinic space group | 分子名称: | CHLORIDE ION, N-{5-[(1R)-1-hydroxyethyl]-1,3-thiazol-2-yl}-alpha-D-mannopyranosylamine, PROTEIN FIMH | 著者 | Brument, S, Sivignon, A, Dumych, T.I, Moreau, N, Roos, G, Guerardel, Y, Chalopin, T, Deniaud, D, Bilyy, R.O, Darfeuille-Michaud, A, Bouckaert, J, Gouin, S.G. | 登録日 | 2013-01-27 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | 主引用文献 | Thiazolylaminomannosides as Potent Antiadhesives of Type 1 Piliated Escherichia Coli Isolated from Crohn'S Disease Patients. J.Med.Chem., 56, 2013
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2K1F
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![BU of 2k1f by Molmil](/molmil-images/mine/2k1f) | SUMO-3 from Drosophila melanogaster (dsmt3) | 分子名称: | CG4494-PA | 著者 | Kumar, D, Misra, J.R, Misra, A.K, Chugh, J, Sharma, S, Hosur, R.V. | 登録日 | 2008-03-03 | 公開日 | 2009-03-10 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR-derived solution structure of SUMO from Drosophila melanogaster (dSmt3). Proteins, 75, 2009
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7ZS7
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![BU of 7zs7 by Molmil](/molmil-images/mine/7zs7) | Crystal structure of human cathepsin L with covalently bound calpain inhibitor VI | 分子名称: | (2S)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2S)-4-methyl-1-oxidanyl-pentan-2-yl]butanamide, ACETATE ION, Cathepsin L, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-05-06 | 公開日 | 2023-05-17 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 2024
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3ZN3
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![BU of 3zn3 by Molmil](/molmil-images/mine/3zn3) | N-terminal domain of S. pombe Cdc23 APC subunit | 分子名称: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 8, MERCURY (II) ION | 著者 | Zhang, Z, Yang, J, Conin, N, Kulkarni, K, Barford, D. | 登録日 | 2013-02-13 | 公開日 | 2013-02-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Four Canonical Tpr Subunits of Human Apc/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a Tpr Suprahelix J.Mol.Biol., 425, 2013
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2JU6
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![BU of 2ju6 by Molmil](/molmil-images/mine/2ju6) | Solid-State Protein Structure Determination with Proton-Detected Triple Resonance 3D Magic-Angle Spinning NMR Spectroscopy | 分子名称: | Immunoglobulin G-binding protein G | 著者 | Zhou, D.H, Shea, J.J, Nieuwkoop, A.J, Franks, W, Wylie, B.J, Mullen, C, Sandoz, D, Rienstra, C.M. | 登録日 | 2007-08-15 | 公開日 | 2007-12-04 | 最終更新日 | 2024-05-29 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Solid-State Protein-Structure Determination with Proton-Detected Triple-Resonance 3D Magic-Angle-Spinning NMR Spectroscopy. Angew.Chem.Int.Ed.Engl., 46, 2007
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3ZQ1
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![BU of 3zq1 by Molmil](/molmil-images/mine/3zq1) | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | 分子名称: | 10 KDA CHAPERONIN, 60 KDA CHAPERONIN, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Chen, D.-H, Madan, D, Weaver, J, Lin, Z, Schroder, G.F, Chiu, W, Rye, H.S. | 登録日 | 2013-03-04 | 公開日 | 2013-06-19 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (15.9 Å) | 主引用文献 | Visualizing Groel/Es in the Act of Encapsulating a Folding Protein Cell(Cambridge,Mass.), 153, 2013
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2JVE
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![BU of 2jve by Molmil](/molmil-images/mine/2jve) | Solution structure of the extracellular domain of Prod1, a protein implicated in proximodistal identity during amphibian limb regeneration | 分子名称: | Prod 1 | 著者 | Garza-Garcia, A, Harris, R, Esposito, D, Driscoll, P.C. | 登録日 | 2007-09-19 | 公開日 | 2008-09-30 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and phylogenetics of Prod1, a member of the three-finger protein superfamily implicated in salamander limb regeneration. Plos One, 4, 2009
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2JWQ
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![BU of 2jwq by Molmil](/molmil-images/mine/2jwq) | G-quadruplex recognition by quinacridines: a SAR, NMR and Biological study | 分子名称: | DNA (5'-D(*DTP*DTP*DAP*DGP*DGP*DGP*DT)-3'), N,N'-(dibenzo[b,j][1,7]phenanthroline-2,10-diyldimethanediyl)dipropan-1-amine | 著者 | Hounsou, C, Guittat, L, Monchaud, D, Jourdan, M, Saettel, N, Mergny, J.L, Teulade-Fichou, M. | 登録日 | 2007-10-23 | 公開日 | 2008-03-25 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | G-Quadruplex Recognition by Quinacridines: a SAR, NMR, and Biological Study ChemMedChem, 2, 2007
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5UFY
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![BU of 5ufy by Molmil](/molmil-images/mine/5ufy) | Structure of Streptococcus pneumoniae peptidoglycan O-acetyltransferase A (OatA) C-terminal catalytic domain | 分子名称: | Acyltransferase, SODIUM ION | 著者 | Sychantha, D, Jones, C, Little, D.J, Moynihan, P.J, Robinson, H, Galley, N.F, Roper, D.I, Dowson, C.G, Howell, P.L, Clarke, A.J. | 登録日 | 2017-01-06 | 公開日 | 2017-10-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA). PLoS Pathog., 13, 2017
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5UGI
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3ZL2
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![BU of 3zl2 by Molmil](/molmil-images/mine/3zl2) | A thiazolyl-mannoside bound to FimH, orthorhombic space group | 分子名称: | N-{5-[(1R)-1-hydroxyethyl]-1,3-thiazol-2-yl}-alpha-D-mannopyranosylamine, PROTEIN FIMH | 著者 | Brument, S, Sivignon, A, Dumych, T.I, Moreau, N, Roos, G, Guerardel, Y, Chalopin, T, Deniaud, D, Bilyy, R.O, Darfeuille-Michaud, A, Bouckaert, J, Gouin, S.G. | 登録日 | 2013-01-27 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.251 Å) | 主引用文献 | Thiazolylaminomannosides as Potent Antiadhesives of Type 1 Piliated Escherichia Coli Isolated from Crohn'S Disease Patients. J.Med.Chem., 56, 2013
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2JP8
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![BU of 2jp8 by Molmil](/molmil-images/mine/2jp8) | Angiotensin 1-7 | 分子名称: | Angiotensin-(1-7) | 著者 | Lula, I, Denadai, A.L, Resende, J.M, de Souza, F.B, de Lima, G.F, Pilo-Veloso, D, Heine, T, Duarte, H.A, Santos, R.A.S, Sinesterra, R.D. | 登録日 | 2007-04-27 | 公開日 | 2007-10-30 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Study of angiotensin-(1-7) vasoactive peptide and its beta-cyclodextrin inclusion complexes: complete sequence-specific NMR assignments and structural studies Peptides, 28, 2007
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3ZQ0
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![BU of 3zq0 by Molmil](/molmil-images/mine/3zq0) | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | 分子名称: | 10 KDA CHAPERONIN, 60 KDA CHAPERONIN, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Chen, D.-H, Madan, D, Weaver, J, Lin, Z, Schroder, G.F, Chiu, W, Rye, H.S. | 登録日 | 2013-03-04 | 公開日 | 2013-06-19 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9.2 Å) | 主引用文献 | Visualizing Groel/Es in the Act of Encapsulating a Folding Protein Cell(Cambridge,Mass.), 153, 2013
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5U35
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![BU of 5u35 by Molmil](/molmil-images/mine/5u35) | Crystal structure of a de novo designed protein with curved beta-sheet | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-METHOXYETHANOL, CHLORIDE ION, ... | 著者 | Oberdorfer, G, Marcos, E, Basanta, B, Chidyausiku, T.M, Sankaran, B, Zwart, P.H, Baker, D. | 登録日 | 2016-12-01 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
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2JYV
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![BU of 2jyv by Molmil](/molmil-images/mine/2jyv) | Human Granulin F | 分子名称: | Granulin-2 | 著者 | Tolkatchev, D, Wang, P, Chen, Z, Xu, P, Ni, F. | 登録日 | 2007-12-19 | 公開日 | 2008-04-22 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities. Protein Sci., 17, 2008
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7ZYN
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![BU of 7zyn by Molmil](/molmil-images/mine/7zyn) | Crystal Structure of EGFR-T790M/C797S in Complex with WZ4002 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | 著者 | Niggenaber, J, Kleinboelting, S, Mueller, M.P, Rauh, D. | 登録日 | 2022-05-25 | 公開日 | 2023-05-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. Acs Med.Chem.Lett., 14, 2023
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7ZYM
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![BU of 7zym by Molmil](/molmil-images/mine/7zym) | Crystal Structure of EGFR-T790M/C797S in Complex with Brigatinib | 分子名称: | 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, Epidermal growth factor receptor | 著者 | Niggenaber, J, Kleinboelting, S, Mueller, M.P, Rauh, D. | 登録日 | 2022-05-25 | 公開日 | 2023-05-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. Acs Med.Chem.Lett., 14, 2023
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7ZYP
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![BU of 7zyp by Molmil](/molmil-images/mine/7zyp) | Crystal Structure of EGFR-T790M/C797S in Complex with Reversible Aminopyrimidine 9 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, propan-2-yl 2-[[4-(4-azanylpiperidin-1-yl)-2-methoxy-phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate | 著者 | Niggenaber, J, Kleinboelting, S, Mueller, M.P, Rauh, D. | 登録日 | 2022-05-25 | 公開日 | 2023-05-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. Acs Med.Chem.Lett., 14, 2023
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5U5M
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![BU of 5u5m by Molmil](/molmil-images/mine/5u5m) | CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-MEDITOPE | 分子名称: | AZIDO-PEG4-MEDITOPE, Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB, ... | 著者 | Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D. | 登録日 | 2016-12-06 | 公開日 | 2018-03-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-Meditope To Be Published
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7ZYQ
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![BU of 7zyq by Molmil](/molmil-images/mine/7zyq) | Crystal Structure of EGFR-T790M/V948R in Complex with Reversible Aminopyrimidine 13 | 分子名称: | CHLORIDE ION, Epidermal growth factor receptor, SODIUM ION, ... | 著者 | Niggenaber, J, Mueller, M.P, Rauh, D. | 登録日 | 2022-05-25 | 公開日 | 2023-05-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. Acs Med.Chem.Lett., 14, 2023
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2K2Y
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![BU of 2k2y by Molmil](/molmil-images/mine/2k2y) | |