6DLE
| Crystal structure of IgLON5 homodimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgLON family member 5 | 著者 | Ranaivoson, F.M, Turk, L.S, Ozkan, E, Montelione, G.T, Comoletti, D. | 登録日 | 2018-06-01 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.994 Å) | 主引用文献 | Structure of a heterodimer of neuronal cell surface proteins Structure, 2019
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3IO1
| Crystal Structure of Aminobenzoyl-glutamate utilization protein from Klebsiella pneumoniae | 分子名称: | Aminobenzoyl-glutamate utilization protein, SODIUM ION, YTTRIUM (III) ION | 著者 | Kumaran, D, Baumann, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-08-13 | 公開日 | 2009-08-25 | 最終更新日 | 2021-02-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of Aminobenzoyl-glutamate utilization protein from Klebsiella pneumoniae To be Published
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6R3O
| Aspergillus niger ferric acid decarboxylase (Fdc) L439G variant in complex with prFMN (purified in the radical form) and phenylpropiolic acid | 分子名称: | 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ... | 著者 | Bailey, S.S, Leys, D. | 登録日 | 2019-03-20 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Atomic description of an enzyme reaction dependent on reversible 1,3-dipolar cycloaddition to be published
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6R3X
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6R42
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6DW5
| SAMHD1 Bound to Gemcitabine-TP in the Catalytic Pocket | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | 著者 | Knecht, K.M, Buzovetsky, O, Schneider, C, Thomas, D, Srikanth, V, Kaderali, L, Tofoleanu, F, Reiss, K, Ferreiros, N, Geisslinger, G, Batista, V.S, Ji, X, Cinatl, J, Keppler, O.T, Xiong, Y. | 登録日 | 2018-06-26 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6R6V
| Structure of recombinant human butyrylcholinesterase in complex with a fluorescent coumarin-based probe | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, ... | 著者 | Brazzolotto, X, Nachon, F, Knez, D, Gobec, S. | 登録日 | 2019-03-28 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes. J Enzyme Inhib Med Chem, 35, 2020
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3IS3
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3IJ2
| Ligand-receptor structure | 分子名称: | Beta-nerve growth factor, Nerve growth factor receptor (TNFR superfamily, member 16) | 著者 | Feng, D, Garcia, K.C. | 登録日 | 2009-08-03 | 公開日 | 2010-01-12 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | 主引用文献 | Molecular and structural insight into proNGF engagement of p75NTR and sortilin. J.Mol.Biol., 396, 2010
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3ITD
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3ILR
| Structure of Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(4-1)-4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid, 4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ... | 著者 | Garron, M.L, Cygler, M, Shaya, D. | 登録日 | 2009-08-07 | 公開日 | 2009-09-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural snapshots of heparin depolymerization by heparin lyase I. J.Biol.Chem., 284, 2009
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6DY1
| Rabbit N-acylethanolamine-hydrolyzing acid amidase (NAAA) with fatty acid (myristate), in presence of Triton X-100 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY}ETHANOL, CHLORIDE ION, ... | 著者 | Gorelik, A, Gebai, A, Illes, K, Piomelli, D, Nagar, B. | 登録日 | 2018-07-01 | 公開日 | 2018-09-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | 主引用文献 | Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6DRF
| Structure of human Retinal Degeneration 3(RD3) Protein | 分子名称: | Protein RD3 | 著者 | Yu, Q, Lim, S, Peshenko, I, Cudia, D, Dizhoor, A.M, Ames, J.B. | 登録日 | 2018-06-11 | 公開日 | 2019-02-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle. J. Biol. Chem., 294, 2019
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6RAN
| Heterodimeric ABC exporter TmrAB in inward-facing wide conformation | 分子名称: | Multidrug resistance ABC transporter ATP-binding and permease protein, Nanobody Nb9F10 | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RBF
| Mucin 2 D3 domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Javitt, G, Fass, D. | 登録日 | 2019-04-10 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains. J.Mol.Biol., 431, 2019
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6RAG
| Heterodimeric ABC exporter TmrAB in inward-facing wide conformation under turnover conditions | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6DXW
| Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) precursor (C126A) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gorelik, A, Gebai, A, Illes, K, Piomelli, D, Nagar, B. | 登録日 | 2018-07-01 | 公開日 | 2018-09-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3IEC
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6R30
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6R3G
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6DZY
| Cryo-EM structure of the ts2-active human serotonin transporter in complex with 15B8 Fab and 8B6 ScFv bound to ibogaine | 分子名称: | (5beta)-12-methoxyibogamine, 15B8 antibody heavy chain, 15B8 antibody light chain, ... | 著者 | Coleman, J.A, Yang, D, Gouaux, E. | 登録日 | 2018-07-05 | 公開日 | 2019-04-24 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Nature, 569, 2019
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6R3N
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6R4R
| Cryo-EM Structure of the PI3-Kinase SH3 Domain Amyloid Fibril | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha | 著者 | Roeder, C, Vettore, N, Mangels, L.N, Gremer, L, Ravelli, R.B.G, Willbold, D, Hoyer, W, Buell, A.K, Schroder, G.F. | 登録日 | 2019-03-23 | 公開日 | 2019-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy. Nat Commun, 10, 2019
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6E07
| Crystal structure of Canton G6PD in complex with structural NADP | 分子名称: | GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Rahighi, S, Mochly-Rosen, D, Wakatsuki, S. | 登録日 | 2018-07-06 | 公開日 | 2018-07-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator. Nat Commun, 9, 2018
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6DZV
| Wild type human serotonin transporter in complex with 15B8 Fab bound to ibogaine in occluded conformation | 分子名称: | (5beta)-12-methoxyibogamine, 15B8 antibody heavy chain, 15B8 antibody light chain, ... | 著者 | Coleman, J.A, Yang, D, Gouaux, E. | 登録日 | 2018-07-05 | 公開日 | 2019-04-24 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Nature, 569, 2019
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