3ILR

Structure of Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product

Summary for 3ILR

• Entry DOI: 10.2210/pdb3ilr/pdb
• Related: 3IKW
• Descriptor: Heparin lyase I, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(4-1)-4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid, 4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: heparin, polysaccharide lyase, beta-jelly roll, lyase
• Biological source: Bacteroides thetaiotaomicron
• Total number of polymer chains: 1
• Total formula weight: 43432.58

Authors

Garron, M.L.,Cygler, M.,Shaya, D. (deposition date: 2009-08-07, release date: 2009-09-29, Last modification date: 2024-02-21)

• Primary citation: Han, Y.H.,Garron, M.L.,Kim, H.Y.,Kim, W.S.,Zhang, Z.,Ryu, K.S.,Shaya, D.,Xiao, Z.,Cheong, C.,Kim, Y.S.,Linhardt, R.J.,Jeon, Y.H.,Cygler, M.; Structural snapshots of heparin depolymerization by heparin lyase I.; J.Biol.Chem., 284:34019-34027, 2009; PubMed: 19801541; DOI: 10.1074/jbc.M109.025338

Experimental method

X-RAY DIFFRACTION (1.5 Å)