6R42

Structure of R504C mutant of Pseudomonas aeruginosa Penicillin-Binding Protein 3 (PBP3) in complex with piperacillin

Summary for 6R42

Entry DOI	10.2210/pdb6r42/pdb
Related	3OC2 3PBO 4KQO 6HZR 6I1E 6R3X 6R40
Descriptor	Peptidoglycan D,D-transpeptidase FtsI, Piperacillin (Open Form) (3 entities in total)
Functional Keywords	penicillin-binding protein, peptidoglycan, transpeptidase, hydrolase
Biological source	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Total number of polymer chains	1
Total formula weight	58492.56
Authors	Bellini, D.,Dowson, C.G. (deposition date: 2019-03-21, release date: 2020-02-19, Last modification date: 2024-01-24)
Primary citation	Bellini, D.,Koekemoer, L.,Newman, H.,Dowson, C.G. Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance. J.Mol.Biol., 431:3501-3519, 2019 Cited by PubMed: 31301409 DOI: 10.1016/j.jmb.2019.07.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation