6R42

Structure of R504C mutant of Pseudomonas aeruginosa Penicillin-Binding Protein 3 (PBP3) in complex with piperacillin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000917	biological_process	division septum assembly
A	0004180	molecular_function	carboxypeptidase activity
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0007049	biological_process	cell cycle
A	0008233	molecular_function	peptidase activity
A	0008360	biological_process	regulation of cell shape
A	0008658	molecular_function	penicillin binding
A	0008955	molecular_function	peptidoglycan glycosyltransferase activity
A	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0043093	biological_process	FtsZ-dependent cytokinesis
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue JPP A 701

Chain	Residue
A	SER294
A	THR487
A	ALA488
A	ARG489
A	TYR498
A	PHE533
A	HOH811
A	HOH831
A	HOH853
A	TYR328
A	VAL333
A	SER349
A	ASN351
A	TYR407
A	TYR409
A	SER485
A	GLY486

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000255|HAMAP-Rule:MF_02080

Chain	Residue	Details
A	SER294

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