6DXW
Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) precursor (C126A)
Summary for 6DXW
| Entry DOI | 10.2210/pdb6dxw/pdb |
| Descriptor | N-acylethanolamine-hydrolyzing acid amidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | endocannabinoid, lipase, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 158173.20 |
| Authors | Gorelik, A.,Gebai, A.,Illes, K.,Piomelli, D.,Nagar, B. (deposition date: 2018-07-01, release date: 2018-09-26, Last modification date: 2023-10-11) |
| Primary citation | Gorelik, A.,Gebai, A.,Illes, K.,Piomelli, D.,Nagar, B. Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proc. Natl. Acad. Sci. U.S.A., 115:E10032-E10040, 2018 Cited by PubMed: 30301806DOI: 10.1073/pnas.1811759115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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