2A6H
 
 | | Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | | 著者 | Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-07-02 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of transcription inhibition by antibiotic streptolydigin.
Mol.Cell, 19, 2005
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2AFA
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272D
 | | PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE | | 分子名称: | DNA (5'-D(*GP*GP*CP*CP*AP*AP*TP*TP*GP*G)-3') | | 著者 | Vlieghe, D, Van Meervelt, L, Dautant, A, Gallois, B, Precigoux, G, Kennard, O. | | 登録日 | 1996-07-09 | | 公開日 | 1996-09-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure.
Science, 273, 1996
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2ABM
 | | Crystal Structure of Aquaporin Z Tetramer Reveals both Open and Closed Water-conducting Channels | | 分子名称: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-O-octyl-beta-D-glucopyranose, ... | | 著者 | Jiang, J, Daniels, B.V, Fu, D. | | 登録日 | 2005-07-15 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel.
J.Biol.Chem., 281, 2006
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2A94
 | | Structure of Plasmodium falciparum lactate dehydrogenase complexed to APADH. | | 分子名称: | ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase | | 著者 | Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L. | | 登録日 | 2005-07-11 | | 公開日 | 2006-01-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
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2A9G
 | | Structure of C406A arginine deiminase in complex with L-arginine | | 分子名称: | ARGININE, Arginine deiminase | | 著者 | Galkin, A, Lu, X, Dunaway-Mariano, D, Herzberg, O. | | 登録日 | 2005-07-11 | | 公開日 | 2005-08-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures Representing the Michaelis Complex and the Thiouronium Reaction Intermediate of Pseudomonas aeruginosa Arginine Deiminase.
J.Biol.Chem., 280, 2005
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2A69
 | | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-07-02 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
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2A68
 | | Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-07-01 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
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2AA3
 | | Crystal structure of Plasmodium vivax lactate dehydrogenase complex with APADH | | 分子名称: | ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase, ... | | 著者 | Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L. | | 登録日 | 2005-07-13 | | 公開日 | 2006-01-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
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2ACI
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1Y7R
 | | 1.7 A Crystal Structure of Protein of Unknown Function SA2161 from Meticillin-Resistant Staphylococcus aureus, Probable Acetyltransferase | | 分子名称: | PHOSPHATE ION, hypothetical protein SA2161 | | 著者 | Qiu, Y, Zhang, R, Collart, F, Holzle, D, Joachimiak, A, Kossiakoff, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-12-09 | | 公開日 | 2005-01-25 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | 1.7A Crystal Structure of Hypothetical Protein SA2161 from Meticillin-Resistant Staphylococcus aureus
To be Published
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1Y7Q
 | | Mammalian SCAN domain dimer is a domain-swapped homologue of the HIV capsid C-terminal domain | | 分子名称: | Zinc finger protein 174 | | 著者 | Ivanov, D, Stone, J.R, Maki, J.L, Collins, T, Wagner, G. | | 登録日 | 2004-12-09 | | 公開日 | 2005-01-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mammalian SCAN Domain Dimer Is a Domain-Swapped Homolog of the HIV Capsid C-Terminal Domain
Mol.Cell, 17, 2005
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1Y2K
 | | Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 3,5-dimethyl-1-(3-nitro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester | | 分子名称: | 1,2-ETHANEDIOL, 3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ... | | 著者 | Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | | 登録日 | 2004-11-22 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Nat.Biotechnol., 23, 2005
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1Y7X
 | | Solution structure of a two-repeat fragment of major vault protein | | 分子名称: | Major vault protein | | 著者 | Kozlov, G, Vavelyuk, O, Minailiuc, O, Banville, D, Gehring, K, Ekiel, I. | | 登録日 | 2004-12-10 | | 公開日 | 2005-12-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a two-repeat fragment of major vault protein.
J.Mol.Biol., 356, 2006
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1YAV
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1YAC
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1YEX
 | | Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin. | | 分子名称: | Alkyl hydroperoxide reductase subunit C, SULFATE ION | | 著者 | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | | 登録日 | 2004-12-28 | | 公開日 | 2005-08-16 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
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1YBD
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1Y1U
 | | Structure of unphosphorylated STAT5a | | 分子名称: | Signal transducer and activator of transcription 5A | | 著者 | Neculai, D, Neculai, A.M, Verrier, S, Straub, K, Klumpp, K, Pfitzner, E, Becker, S. | | 登録日 | 2004-11-19 | | 公開日 | 2005-10-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Structure of the unphosphorylated STAT5a dimer
J.Biol.Chem., 280, 2005
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2ACS
 | | AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE | | 分子名称: | ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D. | | 登録日 | 1994-04-15 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate.
Biochemistry, 33, 1994
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2ACR
 | | AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE | | 分子名称: | ALDOSE REDUCTASE, CACODYLATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D. | | 登録日 | 1994-04-15 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate.
Biochemistry, 33, 1994
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3Q9N
 | | In silico and in vitro co-evolution of a high affinity complementary protein-protein interface | | 分子名称: | CARBAMOYL SARCOSINE, COENZYME A, CoA binding protein, ... | | 著者 | Karanicolas, J, Corn, J.E, Chen, I, Joachimiak, L.A, Dym, O, Chung, S, Albeck, S, Unger, T, Hu, W, Liu, G, Delbecq, S, Montelione, G.T, Spiegel, C, Liu, D, Baker, D, Israel Structural Proteomics Center (ISPC) | | 登録日 | 2011-01-09 | | 公開日 | 2011-04-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A de novo protein binding pair by computational design and directed evolution.
Mol.Cell, 42, 2011
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2ATO
 | | Crystal structure of Human Cathepsin K in complex with myocrisin | | 分子名称: | (S)-(1,2-DICARBOXYETHYLTHIO)GOLD, Cathepsin K, SULFATE ION | | 著者 | Weidauer, E, Yasuda, Y, Biswal, B.K, Kerr, L.D, Cherney, M.M, Gordon, R.E, James, M.N.G, Bromme, D. | | 登録日 | 2005-08-25 | | 公開日 | 2006-08-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S.
Biol.Chem., 388, 2007
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2B3R
 | | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2 | | 分子名称: | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide, SULFATE ION | | 著者 | Liu, L, Song, X, He, D, Komma, C, Kita, A, Verbasius, J.V, Bellamy, H, Miki, K, Czech, M.P, Zhou, G.W. | | 登録日 | 2005-09-20 | | 公開日 | 2005-12-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2alpha.
J.Biol.Chem., 281, 2006
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2B4F
 | | Structure Of A Cold-Adapted Family 8 Xylanase in complex with substrate | | 分子名称: | beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, endo-1,4-beta-xylanase | | 著者 | De Vos, D, Collins, T, Savvides, S.N, Feller, G, Van Beeumen, J.J. | | 登録日 | 2005-09-23 | | 公開日 | 2006-09-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Oligosaccharide binding in family 8 glycosidases: crystal structures of active-site mutants of the beta-1,4-xylanase pXyl from Pseudoaltermonas haloplanktis TAH3a in complex with substrate and product.
Biochemistry, 45, 2006
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