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PDB: 22172 件
1YAC
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THE 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE YCAC GENE PRODUCT FROM ESCHERICHIA COLI REVEALS AN OCTAMERIC HYDROLASE OF UNKNOWN SPECIFICITY
分子名称: YCAC GENE PRODUCT
著者Colovos, C, Cascio, D, Yeates, T.O.
登録日1998-07-29
公開日1999-02-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.8 A crystal structure of the ycaC gene product from Escherichia coli reveals an octameric hydrolase of unknown specificity.
Structure, 6, 1998
1YEX
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Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin.
分子名称: Alkyl hydroperoxide reductase subunit C, SULFATE ION
著者Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B.
登録日2004-12-28
公開日2005-08-16
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
3R62
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Structure of complement regulator Factor H mutant, T1184R.
分子名称: Complement factor H, GLYCEROL
著者Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P.
登録日2011-03-21
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystallographic determination of the disease-associated T1184R variant of the complement Factor H.
Acta Crystallogr.,Sect.D, 67, 2011
1Y7H
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Structural and biochemical studies identify tobacco SABP2 as a methylsalicylate esterase and further implicate it in plant innate immunity, Northeast Structural Genomics Target AR2241
分子名称: THIOCYANATE ION, salicylic acid-binding protein 2
著者Forouhar, F, Yang, Y, Kumar, D, Chen, Y, Fridman, E, Park, S.W, Chiang, Y, Acton, T.B, Montelione, G.T, Pichersky, E, Klessig, D.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2004-12-08
公開日2004-12-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity
Proc.Natl.Acad.Sci.Usa, 102, 2005
1Y1U
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Structure of unphosphorylated STAT5a
分子名称: Signal transducer and activator of transcription 5A
著者Neculai, D, Neculai, A.M, Verrier, S, Straub, K, Klumpp, K, Pfitzner, E, Becker, S.
登録日2004-11-19
公開日2005-10-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structure of the unphosphorylated STAT5a dimer
J.Biol.Chem., 280, 2005
1Y9J
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Solution structure of the rat Sly1 N-terminal domain
分子名称: Sec1 family domain containing protein 1
著者Arac, D, Dulubova, I, Pei, J, Huryeva, I, Grishin, N.V, Rizo, J.
登録日2004-12-15
公開日2005-02-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional Structure of the rSly1 N-terminal Domain Reveals a Conformational Change Induced by Binding to Syntaxin 5.
J.Mol.Biol., 346, 2005
1Y6D
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Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing
分子名称: Phosphorelay protein luxU
著者Ulrich, D.L, Kojetin, D, Bassler, B.L, Cavanagh, J, Loria, J.P.
登録日2004-12-06
公開日2004-12-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing.
J.Mol.Biol., 347, 2005
1YEP
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Structural and biochemical analysis of the link between enzymatic activity and olgomerization in AhpC, a bacterial peroxiredoxin.
分子名称: Alkyl hydroperoxide reductase subunit C, SULFATE ION
著者Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B.
登録日2004-12-28
公開日2005-08-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
1YFQ
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High resolution S. cerevisiae Bub3 mitotic checkpoint protein
分子名称: ACETATE ION, CALCIUM ION, Cell cycle arrest protein BUB3
著者Wilson, D.K, Cerna, D, Chew, E.
登録日2005-01-03
公開日2005-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The 1.1-a structure of the spindle checkpoint protein bub3p reveals functional regions.
J.Biol.Chem., 280, 2005
1YGC
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Short Factor VIIa with a small molecule inhibitor
分子名称: (R)-4-[2-(3-AMINO-BENZENESULFONYLAMINO)-1-(3,5-DIETHOXY-2-FLUOROPHENYL)-2-OXO-ETHYLAMINO]-2-HYDROXY-BENZAMIDINE, CALCIUM ION, Coagulation factor VII, ...
著者Olivero, A.G, Eigenbrot, C, Goldsmith, R, Robarge, K, Artis, D.R, Flygare, J, Rawson, T, Refino, C, Bunting, S, Kirchhofer, D.
登録日2005-01-04
公開日2005-01-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo.
J.Biol.Chem., 280, 2005
1Y9I
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Crystal structure of low temperature requirement C protein from Listeria monocytogenes
分子名称: CALCIUM ION, GLYCEROL, MAGNESIUM ION, ...
著者Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2004-12-15
公開日2004-12-28
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of phosphatidylglycerophosphatase (PGPase), a putative membrane-bound lipid phosphatase, reveals a novel binuclear metal binding site and two "proton wires".
Proteins, 64, 2006
1Z19
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Crystal structure of a lambda integrase(75-356) dimer bound to a COC' core site
分子名称: 33-MER, 5'-D(*CP*TP*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', 5'-D(P*TP*TP*TP*AP*TP*AP*CP*TP*AP*AP*GP*TP*TP*GP*GP*CP*AP*TP*TP*A)-3', ...
著者Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T.
登録日2005-03-03
公開日2005-06-28
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A structural basis for allosteric control of DNA recombination by lambda integrase.
Nature, 435, 2005
1ZFB
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GGC Duplex B-DNA
分子名称: 5'-D(*CP*CP*GP*CP*CP*GP*GP*CP*GP*G)-3', CALCIUM ION
著者Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S.
登録日2005-04-20
公開日2005-05-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献How sequence defines structure: a crystallographic map of DNA structure and conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2N8L
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Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the KH3 RNA target
分子名称: Insulin-like growth factor 2 mRNA-binding protein 1, RNA (5'-R(P*GP*CP*AP*CP*AP*CP*CP*C)-3')
著者Nicastro, G, Candel, A.M, Ramos, A, Hollingworth, D.
登録日2015-10-21
公開日2017-01-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the RNA target GCACACCC
To be Published
2N8M
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Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the KH4 RNA target
分子名称: Insulin-like growth factor 2 mRNA-binding protein 1, RNA (5'-R(P*UP*CP*GP*GP*AP*CP*U)-3')
著者Nicastro, G, Ramos, A, Candel, A, Hollingworth, D.
登録日2015-10-21
公開日2017-01-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the RNA target UCGGACU
To be Published
1ZOF
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Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter Pylori
分子名称: alkyl hydroperoxide-reductase
著者Papinutto, E, Windle, H.J, Cendron, L, Battistutta, R, Kelleher, D, Zanotti, G.
登録日2005-05-13
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter pylori.
Biochim.Biophys.Acta, 1753, 2005
5UPE
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Crystal structure of human NAMPT with isoindoline urea inhibitor compound 5
分子名称: N-{4-[(3-phenylpropyl)carbamoyl]phenyl}-2H-isoindole-2-carboxamide, Nicotinamide phosphoribosyltransferase
著者Longenecker, K.L, Raich, D, Korepanova, A.V.
登録日2017-02-02
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg. Med. Chem. Lett., 27, 2017
2A1X
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Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate
分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, Phytanoyl-CoA dioxygenase
著者Kavanagh, K.L, McDonough, M.A, Searles, T, Butler, D, Bunkoczi, G, von Delft, F, Edwards, A, Arrowsmith, C, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2005-06-21
公開日2005-08-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Human Phytanoyl-CoA 2-Hydroxylase Identifies Molecular Mechanisms of Refsum Disease
J.Biol.Chem., 280, 2005
3SFV
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Crystal structure of the GDP-bound Rab1a S25N mutant in complex with the coiled-coil domain of LidA from Legionella pneumophila
分子名称: GUANOSINE-5'-DIPHOSPHATE, LidA protein, substrate of the Dot/Icm system, ...
著者Yin, K, Lu, D, Zhu, D, Zhang, H, Li, B, Xu, S, Gu, L.
登録日2011-06-14
公開日2012-04-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State
Plos Pathog., 8, 2012
2A1T
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Structure of the human MCAD:ETF E165betaA complex
分子名称: ADENOSINE MONOPHOSPHATE, Acyl-CoA dehydrogenase, medium-chain specific, ...
著者Toogood, H.S, Van Thiel, A, Scrutton, N.S, Leys, D.
登録日2005-06-21
公開日2005-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein
J.Biol.Chem., 280, 2005
2NV5
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Crystal structure of a C-terminal phosphatase domain of Rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, D (PTPRD)
分子名称: PTPRD, PHOSPHATASE
著者Bonanno, J.B, Gilmore, J, Bain, K.T, Iizuka, M, Xu, W, Wasserman, S, Smith, D, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-11-10
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
1ZYG
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Structure of a Supercoiling Responsive DNA Site
分子名称: 5'-D(*CP*AP*AP*CP*CP*CP*GP*GP*GP*TP*TP*G)-3'
著者Bae, S.H, Yun, S.H, Sun, D, Lim, H.M, Choi, B.S.
登録日2005-06-10
公開日2006-05-23
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural and dynamic basis of a supercoiling-responsive DNA element
Nucleic Acids Res., 34, 2006
3SIG
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The X-ray crystal structure of poly(ADP-ribose) glycohydrolase (PARG) bound to ADP-ribose from Thermomonospora curvata
分子名称: [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, poly(ADP-ribose) glycohydrolase
著者Leys, D, Dunstan, M.S.
登録日2011-06-18
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
Nature, 477, 2011
2ABR
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Structure of D280A arginine deiminase with L-arginine forming a S-alkylthiouronium reaction intermediate
分子名称: Arginine deiminase
著者Galkin, A, Lu, X, Dunaway-Mariano, D, Herzberg, O.
登録日2005-07-15
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures Representing the Michaelis Complex and the Thiouronium Reaction Intermediate of Pseudomonas aeruginosa Arginine Deiminase.
J.Biol.Chem., 280, 2005
2ACQ
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AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE
分子名称: 6-O-phosphono-alpha-D-glucopyranose, ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D.
登録日1994-04-15
公開日1994-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate.
Biochemistry, 33, 1994

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