2A1X

Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate

Summary for 2A1X

Entry DOI	10.2210/pdb2a1x/pdb
Descriptor	Phytanoyl-CoA dioxygenase, FE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total)
Functional Keywords	beta jelly roll, double-stranded beta-helix, structural genomics, structural genomics consortium, sgc, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Peroxisome: O14832
Total number of polymer chains	1
Total formula weight	35692.61
Authors	Kavanagh, K.L.,McDonough, M.A.,Searles, T.,Butler, D.,Bunkoczi, G.,von Delft, F.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,Schofield, C.J.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2005-06-21, release date: 2005-08-16, Last modification date: 2024-02-14)
Primary citation	McDonough, M.A.,Kavanagh, K.L.,Butler, D.,Searles, T.,Oppermann, U.,Schofield, C.J. Structure of Human Phytanoyl-CoA 2-Hydroxylase Identifies Molecular Mechanisms of Refsum Disease J.Biol.Chem., 280:41101-41110, 2005 Cited by PubMed: 16186124 DOI: 10.1074/jbc.M507528200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation