2A1X

Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001561	biological_process	fatty acid alpha-oxidation
A	0003824	molecular_function	catalytic activity
A	0005515	molecular_function	protein binding
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0006103	biological_process	2-oxoglutarate metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006720	biological_process	isoprenoid metabolic process
A	0008198	molecular_function	ferrous iron binding
A	0019606	biological_process	2-oxobutyrate catabolic process
A	0031406	molecular_function	carboxylic acid binding
A	0031418	molecular_function	L-ascorbic acid binding
A	0046872	molecular_function	metal ion binding
A	0048244	molecular_function	phytanoyl-CoA dioxygenase activity
A	0051213	molecular_function	dioxygenase activity
A	0097089	biological_process	methyl-branched fatty acid metabolic process
A	0097731	cellular_component	9+0 non-motile cilium

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 A 450

Chain	Residue
A	HIS175
A	ASP177
A	HIS264
A	AKG451
A	HOH463

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AKG A 451

Chain	Residue
A	ASP177
A	TRP193
A	HIS264
A	SER266
A	ARG275
A	FE2450
A	HOH463
A	LYS120
A	MET157
A	ILE159
A	HIS175

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:16186124

Chain	Residue	Details
A	LYS120
A	MET157
A	HIS175
A	ASP177
A	TRP193
A	HIS264
A	SER266
A	ARG275

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:O35386

Chain	Residue	Details
A	LYS59
A	LYS108
A	LYS231
A	LYS252

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER317

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