2A1X

Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001561	biological_process	fatty acid alpha-oxidation
A	0003824	molecular_function	catalytic activity
A	0005515	molecular_function	protein binding
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0006103	biological_process	2-oxoglutarate metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006720	biological_process	isoprenoid metabolic process
A	0008198	molecular_function	ferrous iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0019606	biological_process	2-oxobutyrate catabolic process
A	0031406	molecular_function	carboxylic acid binding
A	0031418	molecular_function	L-ascorbic acid binding
A	0046872	molecular_function	metal ion binding
A	0048244	molecular_function	phytanoyl-CoA dioxygenase activity
A	0051213	molecular_function	dioxygenase activity
A	0097089	biological_process	methyl-branched fatty acid metabolic process
A	0097731	cellular_component	9+0 non-motile cilium

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 A 450

Chain	Residue
A	HIS175
A	ASP177
A	HIS264
A	AKG451
A	HOH463

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AKG A 451

Chain	Residue
A	ASP177
A	TRP193
A	HIS264
A	SER266
A	ARG275
A	FE2450
A	HOH463
A	LYS120
A	MET157
A	ILE159
A	HIS175

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16186124","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"O35386","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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