3SIG

The X-ray crystal structure of poly(ADP-ribose) glycohydrolase (PARG) bound to ADP-ribose from Thermomonospora curvata

Summary for 3SIG

• Entry DOI: 10.2210/pdb3sig/pdb
• Related: 3SIH 3SII 3SIJ
• Descriptor: poly(ADP-ribose) glycohydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total)
• Functional Keywords: poly adp ribose, hydrolase
• Biological source: Thermomonospora curvata
• Total number of polymer chains: 1
• Total formula weight: 30323.00

Authors

Leys, D.,Dunstan, M.S. (deposition date: 2011-06-18, release date: 2011-08-24, Last modification date: 2023-09-13)

• Primary citation: Slade, D.,Dunstan, M.S.,Barkauskaite, E.,Weston, R.,Lafite, P.,Dixon, N.,Ahel, M.,Leys, D.,Ahel, I.; The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.; Nature, 477:616-620, 2011; PubMed: 21892188; DOI: 10.1038/nature10404

Experimental method

X-RAY DIFFRACTION (1.28 Å)