3SII

The X-ray crystal structure of poly(ADP-ribose) glycohydrolase bound to the inhibitor ADP-HPD from Thermomonospora curvata

Summary for 3SII

• Entry DOI: 10.2210/pdb3sii/pdb
• Related: 3SIG 3SIH 3SIJ
• Descriptor: poly(ADP-ribose) glycohydrolase, 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE (3 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Thermomonospora curvata
• Total number of polymer chains: 1
• Total formula weight: 30306.02

Authors

Dunstan, M.S.,Leys, D. (deposition date: 2011-06-18, release date: 2011-08-24, Last modification date: 2023-09-13)

• Primary citation: Slade, D.,Dunstan, M.S.,Barkauskaite, E.,Weston, R.,Lafite, P.,Dixon, N.,Ahel, M.,Leys, D.,Ahel, I.; The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.; Nature, 477:616-620, 2011; PubMed: 21892188; DOI: 10.1038/nature10404

Experimental method

X-RAY DIFFRACTION (1.48 Å)