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PDB: 52974 results

6W2G
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BU of 6w2g by Molmil
Crystal Structure of Y188G Variant of the Internal UBA Domain of HHR23A in Monoclinic Unit Cell
Descriptor: 1,2-ETHANEDIOL, UV excision repair protein RAD23 homolog A
Authors:Bowler, B.E, Zeng, B, Becht, D.C, Rothfuss, M, Sprang, S.R, Mou, T.-C.
Deposit date:2020-03-05
Release date:2021-03-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:High-Accuracy Prediction of Stabilizing Surface Mutations to the Three-Helix Bundle, UBA(1), with EmCAST.
J.Am.Chem.Soc., 145, 2023
6VZO
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BU of 6vzo by Molmil
Crystal structure of human PPARgamma ligand binding domain (Protein delipidated by denature and refold)
Descriptor: Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2020-02-28
Release date:2021-03-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
3EHF
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BU of 3ehf by Molmil
Crystal structure of DesKC in complex with AMP-PCP
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Sensor kinase (YocF protein)
Authors:Albanesi, D, Alzari, P.M, Buschiazzo, A.
Deposit date:2008-09-12
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural plasticity and catalysis regulation of a thermosensor histidine kinase
Proc.Natl.Acad.Sci.USA, 106, 2009
6VZM
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BU of 6vzm by Molmil
Crystal structure of human PPARgamma ligand binding domain Y473E mutant in complex with Darglitazone
Descriptor: (5Z)-5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2020-02-28
Release date:2021-03-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
6VZN
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BU of 6vzn by Molmil
Crystal structure of human PPARgamma ligand binding domain Y473E mutant
Descriptor: Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2020-02-28
Release date:2021-03-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
6VZL
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BU of 6vzl by Molmil
Crystal structure of human PPARgamma ligand binding domain in complex with GW1929
Descriptor: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2020-02-28
Release date:2021-03-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
4ILK
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BU of 4ilk by Molmil
Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MANGANESE (II) ION, Starvation sensing protein rspB, ...
Authors:Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K.
Deposit date:2012-12-31
Release date:2013-01-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH
To be Published
1T61
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BU of 1t61 by Molmil
crystal structure of collagen IV NC1 domain from placenta basement membrane
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M.
Deposit date:2004-05-05
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links
J.Biol.Chem., 279, 2004
6W81
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BU of 6w81 by Molmil
Structure of PEDV main protease bound to potent broad-spectrum non-covalent inhibitor X77
Descriptor: MALONIC ACID, N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide, Peptidase C30
Authors:Mesecar, A.D, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-03-20
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A taxonomically-driven approach to development of potent, broad-spectrum inhibitors of coronavirus main protease including SARS-CoV-2 (COVID-19)
To Be Published
3ZN6
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BU of 3zn6 by Molmil
VP16-VP17 complex, a complex of the two major capsid proteins of bacteriophage P23-77
Descriptor: CHLORIDE ION, SODIUM ION, VP16, ...
Authors:Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I.
Deposit date:2013-02-13
Release date:2013-05-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
7AH9
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BU of 7ah9 by Molmil
Substrate-engaged type 3 secretion system needle complex from Salmonella enterica typhimurium - SpaR state 1
Descriptor: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, LAURYL DIMETHYLAMINE-N-OXIDE, Lipoprotein PrgK, ...
Authors:Fahrenkamp, D, Goessweiner-Mohr, N, Miletic, S, Wald, J, Marlovits, T.
Deposit date:2020-09-24
Release date:2021-03-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation
Nat Commun, 12, 2021
3ESL
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BU of 3esl by Molmil
Crystal structure of the conserved N-terminal domain of the mitotic checkpoint component BUB1
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Checkpoint serine/threonine-protein kinase BUB1
Authors:Bolanos-Garcia, V.M, Chirgadze, D.Y, Blundell, T.L.
Deposit date:2008-10-06
Release date:2009-02-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores.
Structure, 17, 2009
3ZUZ
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BU of 3zuz by Molmil
Structure of Shq1p C-terminal domain
Descriptor: ISOPROPYL ALCOHOL, PROTEIN SHQ1
Authors:Walbott, H, Machado-Pinilla, R, Liger, D, Blaud, M, Rety, S, Grozdanov, P.N, Godin, K, vanTilbeurgh, H, Varani, G, Meier, U.T, Leulliot, N.
Deposit date:2011-07-22
Release date:2011-11-30
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The H/Aca Rnp Assembly Factor Shq1 Functions as an RNA Mimic.
Genes Dev., 25, 2011
4RHP
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BU of 4rhp by Molmil
Crystal structure of human COQ9 in complex with a phospholipid, Northeast Structural Genomics Consortium Target HR5043
Descriptor: DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Ubiquinone biosynthesis protein COQ9, mitochondrial
Authors:Forouhar, F, Lew, S, Seetharaman, J, Wang, H, Lee, D, Kogan, S, Maglaqui, M, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
Deposit date:2014-10-02
Release date:2014-10-22
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
6VJO
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BU of 6vjo by Molmil
Human parainfluenza virus type 3 fusion glycoprotein N-terminal heptad repeat domain+alpha/beta-VI
Descriptor: Fusion glycoprotein F0
Authors:Outlaw, V.K, Kreitler, D.F, Gellman, S.H.
Deposit date:2020-01-16
Release date:2021-04-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineering Protease-Resistant Peptides to Inhibit Human Parainfluenza Viral Respiratory Infection.
J.Am.Chem.Soc., 143, 2021
2J1R
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BU of 2j1r by Molmil
Structure of a Streptococcus pneumoniae fucose binding module
Descriptor: CALCIUM ION, FUCOLECTIN-RELATED PROTEIN
Authors:Boraston, A.B, Wang, D, Burke, R.D.
Deposit date:2006-08-15
Release date:2006-09-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Blood Group Antigen Recognition by a Streptococcus Pneumoniae Virulence Factor.
J.Biol.Chem., 281, 2006
3ZN4
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BU of 3zn4 by Molmil
VP16, a capsid protein of bacteriophage P23-77 (VP16-type-2)
Descriptor: CHLORIDE ION, CITRIC ACID, VP16
Authors:Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I.
Deposit date:2013-02-13
Release date:2013-05-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
1JSU
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BU of 1jsu by Molmil
P27(KIP1)/CYCLIN A/CDK2 COMPLEX
Descriptor: CYCLIN A, CYCLIN-DEPENDENT KINASE-2, P27, ...
Authors:Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1996-07-03
Release date:1997-07-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.
Nature, 382, 1996
3ZJ0
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BU of 3zj0 by Molmil
The human O-GlcNAcase C-terminal domain is a pseudo histone acetyltransferase
Descriptor: 1,2-ETHANEDIOL, ACETYL COENZYME *A, ACETYLTRANSFERASE, ...
Authors:Rao, F.V, Schuettelkopf, A.W, Dorfmueller, H.C, Ferenbach, A.T, Navratilova, I, van Aalten, D.M.F.
Deposit date:2013-01-15
Release date:2013-10-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a Bacterial Putative Acetyltransferase Defines the Fold of the Human O-Glcnacase C-Terminal Domain.
Open Biol., 3, 2013
7BOM
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BU of 7bom by Molmil
Crystal structure of recombinant horse spleen apo-R52C/E56C/R59C/E63C-Fr immobilized with gold ions.
Descriptor: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
Authors:Hishikawa, Y, Maity, B, Ito, N, Abe, S, Lu, D, Ueno, T.
Deposit date:2020-03-19
Release date:2021-01-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Design of Multinuclear Gold Binding Site at the Two-fold Symmetric Interface of the Ferritin Cage
Chem Lett., 49, 2021
6WBA
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BU of 6wba by Molmil
Structure of Mouse Importin alpha MLH1- R470A NLS Peptide Complex
Descriptor: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
Authors:de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
Deposit date:2020-03-26
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6WBB
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BU of 6wbb by Molmil
Structure of Mouse Importin alpha - MLH1-E475A NLS peptide complex
Descriptor: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
Authors:De Barros, A.C, Da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
Deposit date:2020-03-26
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.663 Å)
Cite:Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6WBC
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BU of 6wbc by Molmil
Structure of Mouse Importin alpha- MLH1-R472K NLS Peptide Complex
Descriptor: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
Authors:de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
Deposit date:2020-03-26
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
2IJD
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BU of 2ijd by Molmil
Crystal Structure of the Poliovirus Precursor Protein 3CD
Descriptor: Picornain 3C, RNA-directed RNA polymerase, SULFATE ION, ...
Authors:Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
Deposit date:2006-09-29
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase.
J.Virol., 81, 2007
1KB8
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BU of 1kb8 by Molmil
A COMPARISON OF NMR SOLUTION STRUCTURES OF THE RECEPTOR BINDING DOMAINS OF PSEUDOMONAS AERUGINOSA PILI STRAINS PAO, KB7, AND PAK: IMPLICATIONS FOR RECEPTOR BINDING AND SYNTHETIC VACCINE DESIGN
Descriptor: KB7 PILIN, TRANS
Authors:Campbell, A.P, Mcinnes, C, Hodges, R.S, Sykes, B.D.
Deposit date:1995-10-05
Release date:1996-01-29
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Comparison of NMR solution structures of the receptor binding domains of Pseudomonas aeruginosa pili strains PAO, KB7, and PAK: implications for receptor binding and synthetic vaccine design.
Biochemistry, 34, 1995

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