3ESL

Crystal structure of the conserved N-terminal domain of the mitotic checkpoint component BUB1

Summary for 3ESL

• Entry DOI: 10.2210/pdb3esl/pdb
• Descriptor: Checkpoint serine/threonine-protein kinase BUB1, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID (3 entities in total)
• Functional Keywords: bub1, mitotic spindle checkpoint, tpr motif, all-alpha domain, mad3-like domain, chromosome instability, atp-binding, cell cycle, kinase, nucleotide-binding, nucleus, phosphorylation, serine/threonine-protein kinase, transferase, kinetochore localization, phosphoprotein
• Biological source: Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast)
• Cellular location: Nucleus: P41695
• Total number of polymer chains: 2
• Total formula weight: 49177.80

Authors

Bolanos-Garcia, V.M.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2008-10-06, release date: 2009-02-17, Last modification date: 2023-12-27)

• Primary citation: Bolanos-Garcia, V.M.,Kiyomitsu, T.,D'Arcy, S.,Chirgadze, D.Y.,Grossmann, J.G.,Matak-Vinkovic, D.,Venkitaraman, A.R.,Yanagida, M.,Robinson, C.V.,Blundell, T.L.; The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores.; Structure, 17:105-116, 2009; PubMed: 19141287; DOI: 10.1016/j.str.2008.10.015

Experimental method

X-RAY DIFFRACTION (1.74 Å)