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PDB: 45 results

5J3D
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BU of 5j3d by Molmil
Crystal structure of human Fab 14N4 in complex with post-fusion RSV F
Descriptor: 14N4 heavy chain, 14N4 light chain, Fusion glycoprotein F0
Authors:Mousa, J.J, Crowe, J.E.
Deposit date:2016-03-30
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.077 Å)
Cite:Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5WEQ
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BU of 5weq by Molmil
The crystal structure of a MR78 mutant
Descriptor: MR78 mutant Fab heavy chain, MR78 mutant light chain
Authors:Dong, J, Williamson, L.E, Crowe, J.E.
Deposit date:2017-07-10
Release date:2018-04-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25, 2017
4UIH
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BU of 4uih by Molmil
Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation.
Descriptor: ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAIN
Authors:Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe, J.E, Lok, S.-M.
Deposit date:2015-03-30
Release date:2015-07-15
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers.
Science, 349, 2015
6E9I
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BU of 6e9i by Molmil
The crystal structure of bovine ultralong antibody BOV-4
Descriptor: Bovine ultralong antibody BOV-4 heavy chain, Bovine ultralong antibody BOV-4 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9G
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BU of 6e9g by Molmil
The crystal structure of bovine ultralong antibody BOV-2
Descriptor: Bovine ultralong antibody BOV-2 heavy chain, Bovine ultralong antibody BOV-2 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E8V
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BU of 6e8v by Molmil
The crystal structure of bovine ultralong antibody BOV-1
Descriptor: Bovine ultralong antibody BOV-1 Heavy chain, Bovine ultralong antibody BOV-1 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-07-31
Release date:2019-09-04
Last modified:2020-10-21
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9H
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BU of 6e9h by Molmil
The crystal structure of bovine ultralong antibody BOV-3
Descriptor: Bovine ultralong antibody BOV-3 heavy chain, Bovine ultralong antibody BOV-3 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9U
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BU of 6e9u by Molmil
The crystal structure of bovine ultralong antibody BOV-7
Descriptor: Bovine ultralong antibody BOV-7 heavy chain, Bovine ultralong antibody BOV-7 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9K
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BU of 6e9k by Molmil
The crystal structure of bovine ultralong antibody BOV-5
Descriptor: Bovine ultralong antibody BOV-5 heavy chain, IGL@ protein
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Method:X-RAY DIFFRACTION (2.193 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9Q
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BU of 6e9q by Molmil
The crystal structure of bovine ultralong antibody BOV-6
Descriptor: Bovine ultralong antibody BOV-6 heavy chain, Bovine ultralong antibody BOV-6 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6XOB
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BU of 6xob by Molmil
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP with Fab EEEV-143.
Descriptor: EEEV-143 Fab heavy chain, EEEV-143 Fab light chain, Togavirin
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2020-07-06
Release date:2020-12-23
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Cell, 183, 2020
6XO4
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BU of 6xo4 by Molmil
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP
Descriptor: Togavirin
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2020-07-06
Release date:2020-12-23
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Cell, 183, 2020
8EKD
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BU of 8ekd by Molmil
Cryo-EM map of SARS-CoV-2 Omicron BA.2 spike in complex with 2130-1-0114-112
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LLNL-199 HC, Fab LLNL-199 LC, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2022-09-20
Release date:2024-02-21
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Computationally restoring the potency of a clinical antibody against Omicron.
Nature, 629, 2024
5ITB
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BU of 5itb by Molmil
Crystal structure of the anti-RSV F Fab 14N4
Descriptor: anti-RSV F Fab 14N4 Heavy chain, anti-RSV F Fab 14N4 Light chain
Authors:Mousa, J.J, Crowe, J.E.
Deposit date:2016-03-16
Release date:2016-10-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
8DBZ
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BU of 8dbz by Molmil
CryoEM structure of Hantavirus ANDV Gn(H) protein complex with 2Fabs ANDV-5 and ANDV-34
Descriptor: COV44-79 heavy chain constant domain, Fab Fc (L) KappaC, Fv (H) ANDV-34, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2022-06-15
Release date:2023-04-05
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Antigenic mapping and functional characterization of human new world hantavirus neutralizing antibodies.
Elife, 12, 2023
5UQY
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BU of 5uqy by Molmil
Crystal structure of Marburg virus GP in complex with the human survivor antibody MR78
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP1, ...
Authors:Hashiguchi, T, Fusco, M.L, Hastie, K.M, Bomholdt, Z.A, Lee, J.E, Flyak, A.I, Matsuoka, R, Kohda, D, Yanagi, Y, Hammel, M, Crowe, J.E, Saphire, E.O.
Deposit date:2017-02-08
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for Marburg virus neutralization by a cross-reactive human antibody.
Cell, 160, 2015
5ANY
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BU of 5any by Molmil
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
Descriptor: E1, E2, FAB, ...
Authors:Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
Deposit date:2015-09-08
Release date:2015-11-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
5CGY
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BU of 5cgy by Molmil
Fab fragment of Chikungunya virus neutralizing human monoclonal antibody 4J21
Descriptor: Heavy Chain of Fab, Light Chain of Fab
Authors:Long, F, Crowe, J.E, Rossmann, M.G.
Deposit date:2015-07-09
Release date:2015-11-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CHN
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BU of 5chn by Molmil
Fab fragments of chikungunya virus neutralizing human monoclonal antibody 5M16
Descriptor: Antibody 5M16 Fab Heavy Chain, Antibody 5M16 Fab Light Chain
Authors:Long, F, Crowe, J.E, Rossmann, M.G.
Deposit date:2015-07-10
Release date:2015-11-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112, 2015
5TPN
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BU of 5tpn by Molmil
Crystal structure of RSV F in complex with human antibody hRSV90
Descriptor: Fusion glycoprotein F0,Fibritin, hRSV0 light chain, hRSV90 heavy chain
Authors:Mousa, J.J, Crowe, J.E.
Deposit date:2016-10-20
Release date:2017-02-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.141 Å)
Cite:Crystal structure of RSV F in complex with human antibody hRSV90
To Be Published
7SFV
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BU of 7sfv by Molmil
CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2021-10-04
Release date:2022-03-16
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge.
J.Exp.Med., 219, 2022
6WDT
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BU of 6wdt by Molmil
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Descriptor: EV68-228 heavy chain, EV68-228 light chain, viral protein 1, ...
Authors:Fu, J, Vogt, M.R, Klose, T, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-01
Release date:2020-07-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
6WDS
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BU of 6wds by Molmil
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Descriptor: EV68-159 heavy chain, EV68-159 light chain, viral protein 1, ...
Authors:Fu, J, Klose, T, Vogt, M.R, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-01
Release date:2020-07-15
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
4HFW
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BU of 4hfw by Molmil
Anti Rotavirus Antibody
Descriptor: 6-26 Fab Heavy chain, 6-26 Fab Light chain, SULFATE ION
Authors:Spiller, B.W, Aiyegbo, M, Crowe, J.E.
Deposit date:2012-10-05
Release date:2013-05-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore.
Plos One, 8, 2013
6UIG
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BU of 6uig by Molmil
Crystal structure of human monoclonal antibody H7.200 in complex with H7N9 hemagglutinin HA1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H7.200 Fab heavy chain, H7.200 Fab light chain, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-09-30
Release date:2020-10-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface.
J.Clin.Invest., 130, 2020

 

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