5UQY
Crystal structure of Marburg virus GP in complex with the human survivor antibody MR78
Replaces: 3X2DSummary for 5UQY
Entry DOI | 10.2210/pdb5uqy/pdb |
Descriptor | ENVELOPE GLYCOPROTEIN GP1, alpha-D-mannopyranose, ENVELOPE GLYCOPROTEIN GP2, ... (10 entities in total) |
Functional Keywords | glycoprotein, viral protein, antibody, fab, viral protein-immune system complex, viral protein/immune system |
Biological source | Lake Victoria marburgvirus (strain Ravn-87) (MARV) More |
Total number of polymer chains | 16 |
Total formula weight | 412484.12 |
Authors | Hashiguchi, T.,Fusco, M.L.,Hastie, K.M.,Bomholdt, Z.A.,Lee, J.E.,Flyak, A.I.,Matsuoka, R.,Kohda, D.,Yanagi, Y.,Hammel, M.,Crowe, J.E.,Saphire, E.O. (deposition date: 2017-02-08, release date: 2017-03-01, Last modification date: 2023-10-04) |
Primary citation | Hashiguchi, T.,Fusco, M.L.,Bornholdt, Z.A.,Lee, J.E.,Flyak, A.I.,Matsuoka, R.,Kohda, D.,Yanagi, Y.,Hammel, M.,Crowe, J.E.,Saphire, E.O. Structural basis for Marburg virus neutralization by a cross-reactive human antibody. Cell, 160:904-912, 2015 Cited by PubMed: 25723165DOI: 10.1016/j.cell.2015.01.041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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