6LFK
 
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8GTG
 | | Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-I-152 by XFEL | | 分子名称: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N},~{N}-bis(2-methoxyethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | | 著者 | Cho, H.S, Kim, H. | | 登録日 | 2022-09-08 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
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8GTI
 | | Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL | | 分子名称: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N}-butyl-~{N}-(cyclopropylmethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1, ... | | 著者 | Cho, H.S, Kim, H. | | 登録日 | 2022-09-08 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
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8GTM
 | | Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C203 by XFEL | | 分子名称: | 7-(4-bromanyl-2,6-dimethoxy-phenyl)-4,8-dimethyl-~{N},~{N}-bis[4,4,4-tris(fluoranyl)butyl]-1$l^{4},3,5,9-tetrazabicyclo[4.3.0]nona-1(6),2,4,8-tetraen-2-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | | 著者 | Cho, H.S, Kim, H. | | 登録日 | 2022-09-08 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
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6LBX
 | | Crystal structure of HER2 Domain IV and Rb-H2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-2, Repebody (Rb-H2) | | 著者 | Cho, H.S, Cha, J.S. | | 登録日 | 2019-11-15 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2
Comput Struct Biotechnol J, 19, 2021
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6ISJ
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6K74
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6K3L
 | | Crystal structure of CX-4945 bound Cka1 from C. neoformans | | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, CMGC/CK2 protein kinase, SULFATE ION | | 著者 | Cho, H.S, Yoo, Y. | | 登録日 | 2019-05-20 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural analysis of fungal pathogenicity-related casein kinase alpha subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans.
Sci Rep, 9, 2019
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6K77
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6ISE
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6KO6
 | | Crystal structure of AMPPNP bound Cka1 from C. neoformans | | 分子名称: | CMGC/CK2 protein kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Cho, H.S, Yoo, Y. | | 登録日 | 2019-08-08 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural analysis of fungal pathogenicity-related casein kinase alpha subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans.
Sci Rep, 9, 2019
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6JJL
 | | Crystal structure of the DegP dodecamer with a modulator | | 分子名称: | CYS-TYR-ARG-LYS-LEU, Periplasmic serine endoprotease DegP | | 著者 | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | 登録日 | 2019-02-26 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy.
Commun Biol, 3, 2020
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6JJO
 | | Crystal structure of the DegP dodecamer with a modulator | | 分子名称: | Periplasmic serine endoprotease DegP, TMB-CYRKL modulator | | 著者 | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | 登録日 | 2019-02-26 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.157 Å) | | 主引用文献 | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
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6JJK
 | | Crystal structure of the DegP dodecamer with a modulator | | 分子名称: | CYS-TYR-TYR-LYS-ILE, Periplasmic serine endoprotease DegP | | 著者 | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | 登録日 | 2019-02-26 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
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1J97
 | | Phospho-Aspartyl Intermediate Analogue of Phosphoserine phosphatase | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Phosphoserine Phosphatase | | 著者 | Cho, H, Wang, W, Kim, R, Yokota, H, Damo, S, Kim, S.-H, Wemmer, D, Kustu, S, Yan, D, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2001-05-24 | | 公開日 | 2001-07-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase.
Proc.Natl.Acad.Sci.USA, 98, 2001
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7E5B
 | | Crystal structure of ASC PYD Domain and Rb-B7 | | 分子名称: | Apoptosis-associated speck-like protein containing a CARD, GLYCEROL, Repebody (Rb-B7) | | 著者 | Cho, H.S, Cha, J.S. | | 登録日 | 2021-02-18 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space.
Cell Death Discov, 9, 2023
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7COX
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1DJM
 | | SOLUTION STRUCTURE OF BEF3-ACTIVATED CHEY FROM ESCHERICHIA COLI | | 分子名称: | CHEMOTAXIS PROTEIN Y | | 著者 | Cho, H.S, Lee, S.Y, Yan, D, Pan, X, Parkinson, J.S, Kustu, S, Wemmer, D.E, Pelton, J.G. | | 登録日 | 1999-12-03 | | 公開日 | 2000-04-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of activated CheY.
J.Mol.Biol., 297, 2000
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8OHM
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1H1V
 | | gelsolin G4-G6/actin complex | | 分子名称: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | | 著者 | Choe, H, Burtnick, L.D, Mejillano, M, Yin, H.L, Robinson, R.C, Choe, S. | | 登録日 | 2002-07-23 | | 公開日 | 2003-01-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The Calcium Activation of Gelsolin:Insights from the 3A Structure of the G4-G6/Actin Complex
J.Mol.Biol., 324, 2002
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1L63
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1L55
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1L56
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1L60
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1L61
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