7E5B

Crystal structure of ASC PYD Domain and Rb-B7

Summary for 7E5B

Entry DOI	10.2210/pdb7e5b/pdb
Descriptor	Repebody (Rb-B7), Apoptosis-associated speck-like protein containing a CARD, GLYCEROL, ... (4 entities in total)
Functional Keywords	inflammasome, apoptosis, protein binding
Biological source	Cyclostomata More
Total number of polymer chains	4
Total formula weight	80329.89
Authors	Cho, H.S.,Cha, J.S. (deposition date: 2021-02-18, release date: 2022-03-02, Last modification date: 2023-11-29)
Primary citation	Yu, T.G.,Cha, J.S.,Kim, G.,Sohn, Y.K.,Yoo, Y.,Kim, U.,Song, J.J.,Cho, H.S.,Kim, H.S. Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space. Cell Death Discov, 9:142-142, 2023 Cited by PubMed: 37120628 DOI: 10.1038/s41420-023-01438-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation