6K3L

Crystal structure of CX-4945 bound Cka1 from C. neoformans

Summary for 6K3L

Entry DOI	10.2210/pdb6k3l/pdb
Descriptor	CMGC/CK2 protein kinase, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, SULFATE ION, ... (4 entities in total)
Functional Keywords	kinase, transferase
Biological source	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
Total number of polymer chains	1
Total formula weight	40026.80
Authors	Cho, H.S.,Yoo, Y. (deposition date: 2019-05-20, release date: 2019-11-06, Last modification date: 2023-11-22)
Primary citation	Ong, B.X.,Yoo, Y.,Han, M.G.,Park, J.B.,Choi, M.K.,Choi, Y.,Shin, J.S.,Bahn, Y.S.,Cho, H.S. Structural analysis of fungal pathogenicity-related casein kinase alpha subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans. Sci Rep, 9:14398-14398, 2019 Cited by PubMed: 31591414 DOI: 10.1038/s41598-019-50678-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.09 Å)

Structure validation