8OHM
CRYSTAL STRUCTURE OF RNA HELICASE FROM GENOTYPE 1B HEPATITIS C VIRUS: MECHANISM OF UNWINDING DUPLEX RNA
Summary for 8OHM
| Entry DOI | 10.2210/pdb8ohm/pdb |
| Descriptor | RNA HELICASE (2 entities in total) |
| Functional Keywords | rna helicase, hepatitis c virus, hcv, unwinding mechanism, helicase |
| Biological source | Hepatitis C virus |
| Cellular location | Core protein p21: Host endoplasmic reticulum membrane; Single-pass membrane protein. Core protein p19: Virion . Envelope glycoprotein E1: Virion membrane ; Single-pass type I membrane protein . Envelope glycoprotein E2: Virion membrane ; Single-pass type I membrane protein . p7: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Protease NS2-3: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Single-pass type I membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 5A: Host endoplasmic reticulum membrane ; Peripheral membrane protein . RNA-directed RNA polymerase: Host endoplasmic reticulum membrane ; Single-pass type I membrane protein : P26663 |
| Total number of polymer chains | 1 |
| Total formula weight | 46602.85 |
| Authors | Cho, H.S.,Ha, N.C.,Kang, L.W.,Oh, B.H. (deposition date: 1998-03-13, release date: 1999-04-20, Last modification date: 2024-02-14) |
| Primary citation | Cho, H.S.,Ha, N.C.,Kang, L.W.,Chung, K.M.,Back, S.H.,Jang, S.K.,Oh, B.H. Crystal structure of RNA helicase from genotype 1b hepatitis C virus. A feasible mechanism of unwinding duplex RNA. J.Biol.Chem., 273:15045-15052, 1998 Cited by PubMed: 9614113DOI: 10.1074/jbc.273.24.15045 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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