8IXH
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8IWQ
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8IX9
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8IXM
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8IWG
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7Q5R
| Protein community member pyruvate dehydrogenase complex E2 core from C. thermophilum | 分子名称: | Acetyltransferase component of pyruvate dehydrogenase complex | 著者 | Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. | 登録日 | 2021-11-04 | 公開日 | 2022-02-02 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | 主引用文献 | Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022
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7Q5Q
| Protein community member oxoglutarate dehydrogenase complex E2 core from C. thermophilum | 分子名称: | Dihydrolipoyllysine-residue succinyltransferase | 著者 | Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. | 登録日 | 2021-11-04 | 公開日 | 2022-02-02 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4.38 Å) | 主引用文献 | Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022
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7Q5S
| Protein community member fatty acid synthase complex from C. thermophilum | 分子名称: | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 3-oxoacyl-[acyl-carrier-protein] reductase | 著者 | Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. | 登録日 | 2021-11-04 | 公開日 | 2022-02-02 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4.47 Å) | 主引用文献 | Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022
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6FJM
| tubulin-Disorazole Z complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Disorazole Z, ... | 著者 | Menchon, G, Prota, A.E, Lucena Agell, D, Bucher, P, Jansen, R, Irschik, H, Mueller, R, Paterson, I, Diaz, J.F, Altmann, K.-H, Steinmetz, M.O. | 登録日 | 2018-01-22 | 公開日 | 2018-05-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin. Nat Commun, 9, 2018
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6FII
| Tubulin-Spongistatin complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Menchon, G, Prota, A.E, Lucena Angell, D, Bucher, P, Mueller, R, Paterson, I, Diaz, J.F, Altmann, K.-H, Steinmetz, M.O. | 登録日 | 2018-01-18 | 公開日 | 2018-05-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin. Nat Commun, 9, 2018
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6FJF
| Tubulin-FcMaytansine complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Menchon, G, Prota, A.E, Lucena Angell, D, Bucher, P, Mueller, R, Paterson, I, Diaz, J.F, Altmann, K.-H, Steinmetz, M.O. | 登録日 | 2018-01-22 | 公開日 | 2018-05-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin. Nat Commun, 9, 2018
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5OSK
| Tubulin-7j complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(2,5-Dimethoxybenzyl)-7-sulfamoyloxy-6-methoxy-3,4-dihydroquinazolin-2(1H)-one, CALCIUM ION, ... | 著者 | Menchon, G, Prota, A.E, Steinmetz, M.O, Potter, B.V.L. | 登録日 | 2017-08-17 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure. J. Med. Chem., 61, 2018
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5OV7
| tubulin - rigosertib complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | 著者 | Menchon, G, Prota, A.E, Steinmetz, M, Jost, M. | 登録日 | 2017-08-28 | 公開日 | 2017-10-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Mol. Cell, 68, 2017
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8BX1
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7B9S
| Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | 分子名称: | EccB5, EccC5, EccD5, ... | 著者 | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | 登録日 | 2020-12-14 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the mycobacterial ESX-5 type VII secretion system pore complex. Sci Adv, 7, 2021
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8BX2
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7B9F
| Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | 分子名称: | EccB5, EccC5, EccD5, ... | 著者 | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | 登録日 | 2020-12-14 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the mycobacterial ESX-5 type VII secretion system pore complex. Sci Adv, 7, 2021
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1EA2
| Pseudoreversion of the Catalytic Activity of Y14F by the Additional Tyrosine-to-Phenylalanine Substitution(s) in the Hydrogen Bond Network of Delta-5-3-Ketosteroid Isomerase from Pheudomonas putida Biotype B | 分子名称: | STEROID DELTA-ISOMERASE | 著者 | Choi, G, Ha, N.-C, Kim, M.-S, Hong, B.-H, Choi, K.Y. | 登録日 | 2000-11-03 | 公開日 | 2001-11-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Pseudoreversion of the Catalytic Activity of Y14F by the Additional Substitution(S) of Tyrosine with Phenylalanine in the Hydrogen Bond Network of Delta (5)-3-Ketosteroid Isomerase from Pseudomonas Putida Biotype B Biochemistry, 40, 2001
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1CQS
| CRYSTAL STRUCTURE OF D103E MUTANT WITH EQUILENINEOF KSI IN PSEUDOMONAS PUTIDA | 分子名称: | EQUILENIN, PROTEIN : KETOSTEROID ISOMERASE | 著者 | Choi, G, Ha, N.C, Kim, S.W, Kim, D.H, Park, S, Oh, B.H, Choi, K.Y. | 登録日 | 1999-08-11 | 公開日 | 2003-06-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly
in the catalytic mechanism of Delta 5-3-ketosteroid isomerase from
Pseudomonas putida biotype B Biochemistry, 39, 2000
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2ES0
| Structure of the regulator of G-protein signaling domain of RGS6 | 分子名称: | regulator of G-protein signalling 6 | 著者 | Schoch, G.A, Phillips, C, Turnbull, A, Niesen, F, Johansson, C, Elkins, J.M, Longman, E, Gilealdi, C, Sobott, F, Ball, L, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2005-10-25 | 公開日 | 2005-11-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3H52
| Crystal structure of the antagonist form of human glucocorticoid receptor | 分子名称: | 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, GLYCEROL, Glucocorticoid receptor, ... | 著者 | Schoch, G.A, Benz, J, D'Arcy, B, Stihle, M, Burger, D, Thoma, R, Ruf, A. | 登録日 | 2009-04-21 | 公開日 | 2009-12-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular switch in the glucocorticoid receptor: active and passive antagonist conformations J.Mol.Biol., 395, 2010
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1LN6
| STRUCTURE OF BOVINE RHODOPSIN (Metarhodopsin II) | 分子名称: | RETINAL, RHODOPSIN | 著者 | Choi, G, Landin, J, Galan, J.F, Birge, R.R, Albert, A.D, Yeagle, P.L. | 登録日 | 2002-05-03 | 公開日 | 2002-07-10 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural studies of metarhodopsin II, the activated form of the G-protein coupled receptor, rhodopsin. Biochemistry, 41, 2002
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1ZV4
| Structure of the Regulator of G-Protein Signaling 17 (RGSZ2) | 分子名称: | Regulator of G-protein signaling 17 | 著者 | Schoch, G.A, Jansson, A, Elkins, J.M, Haroniti, A, Niesen, F.H, Bunkoczi, G, Lee, W.H, Turnbull, A.P, Yang, X, Sundstrom, M, Arrowsmith, C, Edwards, A, Marsden, B, Gileadi, O, Ball, L, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2005-06-01 | 公開日 | 2005-06-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2A72
| Structure of the regulator of G-protein signaling domain of RGS7 | 分子名称: | CHLORIDE ION, Regulator of G-protein signalling 7 | 著者 | Schoch, G.A, Johansson, C, Phillips, C, Debreczeni, J, Smee, C, Elkins, J.M, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Gileadi, O, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2005-07-04 | 公開日 | 2005-07-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3MNE
| Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by F608S mutation at 1.96A | 分子名称: | DEXAMETHASONE, GLYCEROL, Glucocorticoid receptor, ... | 著者 | Schoch, G.A, Seitz, T, Benz, J, Banner, D, Stihle, M, D'Arcy, B, Thoma, R, Sterner, R, Hennig, M, Ruf, A. | 登録日 | 2010-04-21 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. J.Mol.Biol., 403, 2010
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