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6FII

Tubulin-Spongistatin complex

Summary for 6FII
Entry DOI10.2210/pdb6fii/pdb
DescriptorTubulin alpha-1B chain, GLYCEROL, DIMETHYL SULFOXIDE, ... (14 entities in total)
Functional Keywordscell cycle, tubulin fold, cytoskeleton, microtubule
Biological sourceRattus norvegicus (Rat)
More
Total number of polymer chains6
Total formula weight265992.48
Authors
Menchon, G.,Prota, A.E.,Lucena Angell, D.,Bucher, P.,Mueller, R.,Paterson, I.,Diaz, J.F.,Altmann, K.-H.,Steinmetz, M.O. (deposition date: 2018-01-18, release date: 2018-05-30, Last modification date: 2024-01-17)
Primary citationMenchon, G.,Prota, A.E.,Lucena-Agell, D.,Bucher, P.,Jansen, R.,Irschik, H.,Muller, R.,Paterson, I.,Diaz, J.F.,Altmann, K.H.,Steinmetz, M.O.
A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.
Nat Commun, 9:2106-2106, 2018
Cited by
PubMed: 29844393
DOI: 10.1038/s41467-018-04535-8
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.405 Å)
Structure validation

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