2A72

Structure of the regulator of G-protein signaling domain of RGS7

Summary for 2A72

• Entry DOI: 10.2210/pdb2a72/pdb
• Descriptor: Regulator of G-protein signalling 7, CHLORIDE ION (3 entities in total)
• Functional Keywords: human rgs7, regulator of g-protein signaling 7, gtpase-activating proteins (gap), structural genomics, structural genomics consortium, sgc, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytosol : P49802
• Total number of polymer chains: 2
• Total formula weight: 34312.20

Authors

Schoch, G.A.,Johansson, C.,Phillips, C.,Debreczeni, J.,Smee, C.,Elkins, J.M.,Sundstrom, M.,Edwards, A.,Arrowsmith, C.,von Delft, F.,Gileadi, O.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2005-07-04, release date: 2005-07-12, Last modification date: 2024-04-03)

• Primary citation: Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.; Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.; Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008; PubMed: 18434541; DOI: 10.1073/pnas.0801508105

Experimental method

X-RAY DIFFRACTION (2 Å)