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PDB: 480 件
8HAZ
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Crystal structure of Caenorhabditis elegans NMAD-1 in complex with ligand I
分子名称: DNA N6-methyl adenine demethylase, SULFATE ION
著者Shang, G, Chen, Z.
登録日2022-10-27
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A.
Int J Mol Sci, 25, 2024
8HBB
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Crystal structure of Caenorhabditis elegans NMAD-1 in complex with ligand III
分子名称: CHLORIDE ION, DNA N6-methyl adenine demethylase, MANGANESE (II) ION
著者Shang, G, Chen, Z.
登録日2022-10-27
公開日2024-02-07
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A.
Int J Mol Sci, 25, 2024
8HB2
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Crystal structure of Caenorhabditis elegans NMAD-1 in complex with ligand II
分子名称: 2-OXOGLUTARIC ACID, DNA N6-methyl adenine demethylase, MANGANESE (II) ION
著者Shang, G, Chen, Z.
登録日2022-10-27
公開日2024-02-07
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A.
Int J Mol Sci, 25, 2024
1GG4
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI UDPMURNAC-TRIPEPTIDE D-ALANYL-D-ALANINE-ADDING ENZYME (MURF) AT 2.3 ANGSTROM RESOLUTION
分子名称: UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMYL-2,6-DIAMINOPIMELATE-D-ALANYL-D-ALANYL LIGASE
著者Yan, Y, Munshi, S, Chen, Z.
登録日2000-07-12
公開日2000-12-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 A resolution.
J.Mol.Biol., 304, 2000
2BPV
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HIV-1 protease-inhibitor complex
分子名称: 1-[2-HYDROXY-4-(2-HYDROXY-5-METHYL-CYCLOPENTYLCARBAMOYL)5-PHENYL-PENTYL]-4-(3-PYRIDIN-3-YL-PROPIONYL)-PIPERAZINE-2-CARB OXYLIC ACID TERT-BUTYLAMIDE, HIV-1 PROTEASE
著者Munshi, S, Chen, Z.
登録日1998-01-22
公開日1999-02-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
2BPY
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HIV-1 protease-inhibitor complex
分子名称: HIV-1 PROTEASE, N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[(2(S)-TERTIARY-BUTYLAMINO-CARBONYL)-4-(N1-(2)-(N-METHYLPIPERAZINYL)-3-CHLORO-PYRAZINYL-5-CARBONYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYL-PENTANAMIDE
著者Munshi, S, Chen, Z.
登録日1998-01-22
公開日1999-02-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
2BPZ
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HIV-1 protease-inhibitor complex
分子名称: HIV-1 PROTEASE, N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[(2(S)-TERTIARY-BUTYLAMINO-CARBONYL)-4-(N1-(2)-(N-METHYLPIPERAZINYL)-3-CHLORO-PYRAZINYL-5-CARBONYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYL-PENTANAMIDE
著者Munshi, S, Chen, Z.
登録日1998-01-22
公開日1999-02-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
2BPX
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HIV-1 protease-inhibitor complex
分子名称: HIV-1 PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
著者Munshi, S, Chen, Z.
登録日1998-01-22
公開日1999-02-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
2BPW
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HIV-1 protease-inhibitor complex
分子名称: 1-[2-HYDROXY-4-(2-HYDROXY-5-METHYL-CYCLOPENTYLCARBAMOYL)5-PHENYL-PENTYL]-4-(3-PYRIDIN-3-YL-PROPIONYL)-PIPERAZINE-2-CARB OXYLIC ACID TERT-BUTYLAMIDE, HIV-1 PROTEASE
著者Munshi, S, Chen, Z.
登録日1998-01-22
公開日1999-02-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
8H34
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Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 hexameric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-07
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.99 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H33
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Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 tetrameric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-07
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.86 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H3Q
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Cryo-EM Structure of the CAND1-Cul3-Rbx1 complex
分子名称: Cullin-3, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-09
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H3A
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Cryo-EM Structure of the KBTBD2-CRL3~N8(removed)-CSN complex
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-08
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.51 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H3F
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Cryo-EM Structure of the KBTBD2-CRL3-CSN complex
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-08
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (6.73 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
5X07
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BU of 5x07 by Molmil
Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site
分子名称: DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta
著者Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y.
登録日2017-01-20
公開日2017-08-16
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site
Biochemistry, 56, 2017
3BEI
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Crystal structure of the slow form of thrombin in a self_inhibited conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Prothrombin
著者Gandhi, P.S, Chen, Z, Mathews, F.S, Di Cera, E.
登録日2007-11-19
公開日2007-12-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural identification of the pathway of long-range communication in an allosteric enzyme.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1T3X
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Three Crystal Structures of Human Coactosin-like Protein
分子名称: Coactosin-like protein
著者Liu, L, Wei, Z, Chen, Z, Wang, Y.
登録日2004-04-28
公開日2005-08-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three Crystal Structures of Human Coactosin-like Protein
TO BE PUBLISHED
1T3Y
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Three Crystal Structures of Human Coactosin-like Protein
分子名称: Coactosin-like protein
著者Liu, L, Wei, Z, Chen, Z, Wang, Y.
登録日2004-04-28
公開日2005-08-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Three Crystal Structures of Human Coactosin-like Protein
To be Published
7BWT
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BU of 7bwt by Molmil
SopD-Rab8 complex structure
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jiang, K, Tong, M, Chen, Z, Gao, X.
登録日2020-04-16
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response.
Nat Microbiol, 6, 2021
1TQF
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Crystal structure of human Beta secretase complexed with inhibitor
分子名称: 3-{2-[(5-AMINOPENTYL)AMINO]-2-OXOETHOXY}-5-({[1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)PHENYL PHENYLMETHANESULFONATE, Beta-secretase 1
著者Munshi, S, Chen, Z, Kuo, L.
登録日2004-06-17
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases.
J.Med.Chem., 47, 2004
4XXB
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Crystal structure of human MDM2-RPL11
分子名称: 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ...
著者Zheng, J, Chen, Z.
登録日2015-01-30
公開日2015-08-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation
Genes Dev., 29, 2015
3JZ1
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Crystal structure of human thrombin mutant N143P in E:Na+ form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, NITRATE ION, ...
著者Niu, W, Chen, Z, Bush-Pelc, L.A, Bah, A, Gandhi, P.S, Di Cera, E.
登録日2009-09-22
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mutant N143P reveals how Na+ activates thrombin
J.Biol.Chem., 284, 2009
3K3N
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Crystal structure of the catalytic core domain of human PHF8
分子名称: FE (II) ION, PHD finger protein 8
著者Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z.
登録日2009-10-03
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into a novel histone demethylase PHF8
Cell Res., 20, 2010
3JZ2
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Crystal structure of human thrombin mutant N143P in E* form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Thrombin heavy chain, ...
著者Niu, W, Chen, Z, Bush-Pelc, L.A, Bah, A, Gandhi, P.S, Di Cera, E.
登録日2009-09-22
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mutant N143P reveals how Na+ activates thrombin
J.Biol.Chem., 284, 2009
3K3O
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BU of 3k3o by Molmil
Crystal structure of the catalytic core domain of human PHF8 complexed with alpha-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, PHD finger protein 8
著者Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z.
登録日2009-10-03
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into a novel histone demethylase PHF8
Cell Res., 20, 2010

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件を2024-06-12に公開中

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