3K3O
Crystal structure of the catalytic core domain of human PHF8 complexed with alpha-ketoglutarate
Summary for 3K3O
Entry DOI | 10.2210/pdb3k3o/pdb |
Related | 3K3N |
Descriptor | PHD finger protein 8, 2-OXOGLUTARIC ACID, FE (II) ION, ... (4 entities in total) |
Functional Keywords | phf8 (phd finger protein 8), histone demethylase, chromatin modification, methylated h3k9, mental retardation, metal-binding, phosphoprotein, zinc-finger, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 43481.29 |
Authors | |
Primary citation | Yu, L.,Wang, Y.,Huang, S.,Wang, J.,Deng, Z.,Zhang, Q.,Wu, W.,Zhang, X.,Liu, Z.,Gong, W.,Chen, Z. Structural insights into a novel histone demethylase PHF8 Cell Res., 20:166-173, 2010 Cited by PubMed: 20101266DOI: 10.1038/cr.2010.8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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