3K3O

Crystal structure of the catalytic core domain of human PHF8 complexed with alpha-ketoglutarate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PHD finger protein 8	polymer	371	43279.3	1	UniProt (Q5JPR9) Pfam (PF02373) Pfam (PF17811) UniProt (by SIFTS) (Q9UPP1) In PDB	Homo sapiens (human)	PHF8
2	A	2-OXOGLUTARIC ACID	non-polymer		146.1	1	Chemie (AKG)
3	A	FE (II) ION	non-polymer		55.8	1	Chemie (FE2)
4		water	water		18.0	109	Chemie (HOH)

Sequence modifications

A: 86 - 447 (UniProt: Q5JPR9)

PDB	External Database	Details
Met 85	-	expression tag
Leu 448	-	expression tag
Glu 449	-	expression tag
His 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43279.3
Non-Polymers*	Number of molecules	2
	Total formula weight	201.9
All*	Total formula weight	43481.3

*Water molecules are not included.